Entecavir CAS 142217-69-4 API Factory High Quality Anti-HBV
Zopanga Zopanga Zokhala ndi Chiyero Chapamwamba ndi Ubwino Wokhazikika
Dzina la Chemical: Entecavir
CAS: 142217-69-4
Mankhwala oletsa ma virus omwe amagwiritsidwa ntchito pochiza matenda a Hepatitis B
API High Quality, Commercial Production
Dzina la Chemical | Entecavir |
Mawu ofanana ndi mawu | 2-Amino-1,9-dihydro-9--[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-imodzi |
Nambala ya CAS | 142217-69-4 |
Nambala ya CAT | RF-API80 |
Stock Status | Mu Stock, Kupanga Kufikira Mazana a Kilogram |
Molecular Formula | C12H15N5O3 |
Kulemera kwa Maselo | 277.28 |
Melting Point | 249.0 ~ 252.0 ℃ |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | White Crystalline Powder |
Chizindikiro cha IR | Kuchuluka kwa mayamwidwe a infraed pachiyeso choyeserera kuyenera kugwirizana ndi muyezo |
Chizindikiro cha HPLC | Nthawi yosungitsa yachiyeso imafanana ndi yanthawi yolozera |
pH | 5.5-7.5 |
Specific Optical Rotation | +24.0°-+28.0° (DMF: MeOH=1:1 C=1%) |
Zogwirizana nazo | |
Zonse Zonyansa | ≤0.30% |
Kusayera Kwambiri Kumodzi | ≤0.10% |
Enantiomer | ≤0.20% |
Zosungunulira Zotsalira | |
Methanol | ≤0.30% |
Dichloromethane | ≤0.06% |
n-Hexane | ≤0.029% |
Tetrahydrofuran | ≤0.072% |
N, N-Dimethylformamide | ≤0.088% |
Toluene | ≤0.089% |
Mkati mwa Madzi | 5.8% ~ 6.5% |
Zotsalira pa Ignition | ≤0.10% |
Zitsulo Zolemera | ≤20ppm |
Kuyesa | 98.0% ~ 102.0% (C12H15N5O3 yowerengedwa pa maziko a anhydrous) |
Tinthu Kukula | D90: ≤100µm |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | API, mankhwala oletsa tizilombo toyambitsa matenda omwe amagwiritsidwa ntchito pochiza matenda a Hepatitis B |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Entecavir ndi mbadwo watsopano wa guanine nucleoside analogues oral mankhwala ochizira matenda a Hepatitis B Virus (HBV), makamaka pofuna kuchiza odwala akuluakulu omwe ali ndi kachilombo ka HIV komanso seramu ya transaminase ikupitiriza kuwonjezeka, kapena minofu ya chiwindi chifukwa cha matenda a chiwindi cha B. , pakali pano ndi kachilombo koyambitsa matenda achangu kwambiri komanso amphamvu kwambiri, kuchuluka kwa masinthidwe otsika kwambiri a nucleoside analogues.Deta imasonyeza kuti osiyana odwala matenda a chiwindi B, kuphatikizapo nucleoside naive ndi nucleoside ankachitira ndi chiwindi matenda enaake odwala, ntchito bwino entecavir mapiritsi mu mankhwala angathe kulamulira matenda mofulumira ndi mosavuta kufika kuchiza chenicheni mapeto, ndicho matenda a chiwindi B osayezedwa;kudzera kumamatira ku chithandizo, gawo lalikulu la odwala likhoza kufika kumapeto kwa chithandizo chamankhwala, chomwe ndi kutembenuka kwa antigen serology, odwala ena amatha kufika pamtundu wa chithandizo chakumapeto, chomwe ndi pamwamba pa antigen negative.