Epalrestat CAS 82159-09-9 Purity>99.5% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. ndiye wopanga wamkulu wa Epalrestat (CAS: 82159-09-9) wokhala ndipamwamba kwambiri.Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, zochepa komanso zochulukirapo zomwe zilipo.Gulani Epalrestat,Please contact: alvin@ruifuchem.com
| Dzina la Chemical | Epalrestat |
| Mawu ofanana ndi mawu | Epalrest;ONO-2235;Ebeth;Kinedak;Sorbistat;(5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-Thiazolidineacetic Acid;2- [(5Z)-5-[(E)-3-Phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic Acid;(E,E) -2--[5-(2-Methyl-3-phenyl-prop-2-enyldene)-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic Acid |
| Stock Status | Mu Stock, Mass Production |
| Nambala ya CAS | 82159-09-9 |
| Molecular Formula | Chithunzi cha C15H13NO3S2 |
| Kulemera kwa Maselo | 319.39 g / mol |
| Melting Point | 222.0 mpaka 226.0 ℃ |
| Kuchulukana | 1.43±0.10 g/cm3 |
| Kusungunuka | DMSO 2 mg/mL Madzi <1 mg/mL Ethanol <1 mg/mL |
| Kusungirako Temp. | Malo Ozizira & Owuma (-20 ℃) |
| COA & MSDS | Likupezeka |
| Gulu | API |
| Mtundu | Ruifu Chemical |
| Zinthu | Miyezo Yoyendera | Zotsatira |
| Maonekedwe | Orange mpaka Orange Red crystalline ufa | Zimagwirizana |
| Chizindikiritso | Zofanana ndi nthawi yosungira ya HPLC yokhazikika | Pitani |
| Melting Point | 222.0 mpaka 226.0 ℃ | 222.4 ~ 224.3 ℃ |
| Kutaya pa Kuyanika | <0.50% | 0.04% |
| Zotsalira pa Ignition | <0.20% | 0.03% |
| Zitsulo Zolemera (Pb) | ≤20ppm | <20ppm |
| Zonse Zonyansa | ≤0.50% | 0.20% |
| Kuyera / Kusanthula Njira | > 99.5% (HPLC) | 99.8% |
| Infrared Spectrum | Zimagwirizana ndi Kapangidwe | Zimagwirizana |
| Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa | |
Phukusi:Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira komanso owuma (-20 ℃) kutali ndi zinthu zosagwirizana.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
Ma ID a UN 2811
WGK Germany 3
RTECS XJ5131855
Kalasi Yowopsa 6.1
Packing Gulu II
Epalrestat (CAS: 82159-09-9) ndi yachiwiri ya aldose reductase inhibitor kuti iwonetsedwe padziko lonse lapansi komanso yoyamba kukhazikitsidwa ku Japan.Epalrestat imagwiritsidwa ntchito pochiza matenda a diabetesic neuropathy.Akufufuzidwanso za matenda ashuga retinopathy ndi nephropathy.Epalrestat ndi aldose reductase inhibitor yokhala ndi IC50 ya 72 nM.
Epalrestat inhibits Aldose Reductase (AR) yomwe imakhudzidwa ndi gawo lochepetsera pakusintha kwa glucose kukhala sorbitol pansi pamikhalidwe ya hyperglycemic.Aldose reductase wakhala chandamale cha ofufuza angapo azachipatala kuti athe kuchiza matenda a shuga a neuropathy ndi retinopathy.Epalrestat ndi mankhwala ovomerezeka ku Japan ndi India, omwe amagwiritsidwa ntchito pochiza matenda a shuga.
Epalrestat imagwiritsidwa ntchito poletsa, kutsitsimutsa, ndi kuchiza zotumphukira zamitsempha ( dzanzi, kupweteka), vibrational paresthesia, ndi vuto la mtima lomwe limakhudzana ndi matenda a shuga.
Epalrestat monga mankhwala ake oimira amachepetsa kuchuluka kwa fructose ndi sorbitol mwa kulepheretsanso ntchito ya aldose reductase, kubwezeretsa Na+-K+-ATPase ndi inositol ntchito, kumawonjezera NO mapangidwe a endothelial maselo, amalepheretsa protein kinase C chizindikiro njira, endothelial cell adhesion. mediated neutrophil ndi endothelial adhesion factor expression komanso amachepetsa zinthu za carboxymethyl lysine mwa odwala matenda ashuga, motero amachiritsa matenda monga shuga ndi zovuta zake.
