Fondaparinux Sodium CAS 114870-03-0 API

Kufotokozera Kwachidule:

Dzina la Chemical: Fondaparinux Sodium

CAS: 114870-03-0

Maonekedwe: Ufa Woyera mpaka Woyera

Kuyesa: 95.0% ~ 103.0% (pa Maziko Ouma)

Antithrombotic Anticoagulant, Factor Xa Inhibitor

Lumikizanani ndi Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Zogwirizana nazo

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Kufotokozera:

Perekani ndi Kuyera Kwambiri ndi Ubwino Wokhazikika
Dzina la Chemical: Fondaparinux Sodium
CAS: 114870-03-0
Antithrombotic Anticoagulant, Factor Xa Inhibitor
API High Quality, Commercial Production

Chemical Properties:

Dzina la Chemical	Fondaparinux Sodium
Nambala ya CAS	114870-03-0
Nambala ya CAT	RF-API84
Stock Status	Mu Stock, Kupanga Kufikira Mazana a Kilogram
Molecular Formula	C31H43N3O49S8.10Na
Kulemera kwa Maselo	1728.08
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Ufa Woyera mpaka Woyera
Njira Yoyesera / Kusanthula	95.0% ~ 103.0% (zouma)
Kusungunuka	Zosungunuka Mwaulere M'madzi, 2.0M Sodium Chloride ndi 0.5M Sodium Hydroxide ndi Insoluble mu Ethanol
Chizindikiritso cha 13C-NMR	Ma resonances a Fondaparinux Sodium ayenera kuwonedwa pa 58.2, 29.5, 60.5, 60.8, 68.9, 69.2, 69.6, 98.9, 100.4, 101.1, 102.4, 103.9, pp.Kusintha kwa Chemical kwa ma siginowa sikusiyana kuposa ± 0.3ppm ma siginecha ena otalika mosiyanasiyana komanso kusintha kwamankhwala, komwe kumachitika chifukwa cha Fondaparinux Sodium, mwina kuwonedwa pakati pa 58.0 ~ 80.5 ppm ndi 98.7 ~ 104.5ppm.
Chizindikiro cha HPLC	Nthawi yosungira pachimake chachikulu chachitsanzo chachitsanzo chikufanana ndi yankho lokhazikika
Chizindikiro cha AAS	Sodium ayenera kukhala ndi khalidwe mayamwidwe pa 330.2nm pansi mtima wa sodium
pH	6.0-8.0
Sodium (Na)	11.5% ~ 15.0% (Yowerengedwa pa anhydrous ndi zosungunulira zaulere)
Sulfate yaulere	≤0.30%
Chloride yotsalira	≤1.00%
Zogwirizana nazo
Chidetso A	≤0.80%
Chidetso B	≤0.60%
Chidetso chimodzi chokha	≤0.30%
Zonse Zonyansa	≤2.00%
Zosungunulira Zotsalira
Methanol	≤3000ppm
Ethanol	≤5000ppm
Ethyl Acetate	≤5000ppm
DMF	≤880ppm
Methylbenzene	≤890ppm
Pyridine	≤50ppm
M'madzi (KF)	≤15.0%
Mabakiteriya Endotoxins	≤3.3EU/mg
Malire a Microbial	Chiwerengero chonse cha Tizilombo ≤100cfu/g
Test Standard	Enterprise Standard;United States Pharmacopoeia (USP) Standard
Kugwiritsa ntchito	API, Antithrombotic Anticoagulant, Factor Xa Inhibitor

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.

Ubwino:

FAQ:

Ntchito:

Fondaparinux Sodium (CAS 114870-03-0) ndiye woyamba mwa gulu latsopano la antithrombotic anticoagulant mankhwala okhudzana ndi ma heparin otsika a molekyulu (LMWH).Fondaparinux sodium ndi factor Xa inhibitor kuti apange malo omangirira kwambiri a anti-coagulant factor antithrombin III (ATIII).Kumanga kwa Fondaparinux sodium pamalowa kumapangitsa kuti ATIII atsekeredwe ndi factor Xa ndi chinthu pafupifupi 300, zomwe zimapangitsa kuti thrombin ikhale yolepheretsa.Imagulitsidwa ndi GlaxoSmithKline.Mtundu wanthawi zonse wopangidwa ndi Alchemia umagulitsidwa ku US ndi Dr. Reddy's Laboratories.Fondaparinux sodium idayambitsidwa koyamba ku US kuti ipewe kutsekeka kwa mitsempha yakuya yomwe ingayambitse kutsekeka kwa m'mapapo pambuyo pa opaleshoni yayikulu ya mafupa.Molekyu yopangidwa kwathunthu ndi kopi ya heparin pentasaccharide motsatizana, chidutswa chachifupi kwambiri chomwe chimatha kuletsa antithrombin lllmediated kuletsa kwa factor Xa potero kulepheretsa kubadwa kwa thrombin popanda antithrombin kanthu.