Fulvestrant (ICI 182780) CAS 129453-61-8 API Factory High Quality

Kufotokozera Kwachidule:

Dzina: Fulvestrant (ICI 182780)

CAS: 129453-61-8

Maonekedwe: Ufa Woyera mpaka Woyera wa Crystalline

Kuyesa: 97.0% ~ 102.0% (zouma)

Fulvestrant amagwiritsidwa ntchito pochiza khansa ya m'mawere yokhudzana ndi mahomoni mwa amayi omwe ali ndi vuto la postmenopausal.

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Kufotokozera:

Zopanga Zopanga Zokhala ndi Chiyero Chapamwamba ndi Ubwino Wokhazikika
Dzina: Fulvestrant
CAS: 129453-61-8
Fulvestrant amagwiritsidwa ntchito pochiza khansa ya m'mawere yokhudzana ndi mahomoni mwa amayi omwe ali ndi vuto la postmenopausal.
API High Quality, Commercial Production

Chemical Properties:

Dzina la Chemical	Fulvestrant
Mawu ofanana ndi mawu	(7α,17β) -7-[9-[(4,4,5,5,5-Pentafluorpentyl)sulfinyl]nonyl]estra-1,3,5(10) -trien-3,17-diol;Mtengo wa ICI 182780
Nambala ya CAS	129453-61-8
Nambala ya CAT	RF-API81
Stock Status	Mu Stock, Kupanga Kufikira Mazana a Kilogram
Molecular Formula	Chithunzi cha C32H47F5O3S
Kulemera kwa Maselo	606.77
Melting Point	104.0 ~ 106.0 ℃
Kusungunuka	Zosungunuka mu Methanol, Ethanol;Zosasungunuka m'madzi
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Ufa Wa Crystalline Woyera mpaka Woyera
Chizindikiritso	Ndi IR, HPLC
Specific Optical Rotation	+ 108.0 ° mpaka +115.0 °
Kutaya pa Kuyanika	≤0.50%
Zotsalira pa Ignition	≤0.10%
6-Keto-Fulvestrant	≤0.10%
6,7-Fulvestrant	≤0.10%
Fulvestrant Sulfone	≤0.20%
Fulvestrant Yowonjezera	≤0.30%
Fulvestrant Sterol Dimmer	≤0.80%
Aliyense Payekha Chodetsedwa Chosadziwika	≤0.10%
Zonse Zonyansa	≤1.0%
Fulvestrant A	42.0% ~ 48.0%
Fulvestrant B	52.0% ~ 58.0%
DMF	≤620ppm
Zitsulo Zolemera	≤10ppm
Kuyesa	97.0% ~ 102.0% (zouma)
Kusungirako	Sungani m'miyendo yotsekedwa bwino yosagwira kuwala yosungidwa mufiriji pa 2 ~ 8 ℃
Test Standard	United States Pharmacopoeia (USP) Standard
Kugwiritsa ntchito	Estrogen Receptor Antagonist

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.

Ubwino:

FAQ:

Ntchito:

Fulvestrant (ICI-182780) CAS 129453-61-8, ndi mankhwala opangira jekeseni wa minofu omwe amapangidwa ndi kampani ya AstraZeneca ndipo amagwiritsidwa ntchito pochiza khansa ya m'mawere yomwe imakhala yovuta kwambiri kwa amayi omwe ali ndi khansa ya m'mawere.Fulvestrant ndi mankhwala okhawo a antiestrogen omwe angagwiritsidwe ntchito kwambiri potsatira chithandizo cha tamoxifen chosapambana.Mankhwalawa ndi amtundu wa endocrine therapy, chifukwa chake sangayambitse zovuta zilizonse zomwe zimachitika mu chemotherapy, ndikupangitsa kuti azitsatira bwino odwala.Mayesero angapo azachipatala apeza kuti 250mg Fulvestrant ndi yothandiza komanso yotetezeka nthawi zonse ngati njira yachiwiri yothandizira khansa ya m'mawere.Fulvestrant ndi wotsutsa wa Estrogen Receptor (ER) wokhala ndi IC50 ya 0.94 nM mu kuyesa kopanda ma cell.Fulvestrant imapangitsanso autophagy ndi apoptosis ndipo imakhala ndi antitumor.