Ganciclovir CAS 82410-32-0 API BW 759 GCV Antiviral CMV Inhibitor High Quality

Ganciclovir (CAS 82410-32-0) ndi ya nucleoside antiviral mankhwala, kukhala mtundu wa zotumphukira za guanosine.Ganciclovir ndi parenterally-yogwira sapha tizilombo toyambitsa matenda anasonyeza kwa maso- kapena zoopsa moyo cytomegalovirus (CMV) matenda odwala immunocompromised.Ili ndi zoletsa zochulukirapo, zoletsa kwambiri pa virus ya nsungu ndipo ndi mankhwala oyamba ochizira matenda a cytomegalovirus omwe ali ndi mphamvu yolimbana ndi kachilombo ka hepatitis B ndi adenovirus.Ndi homologue ya acyclovir (ACV) yokhala ndi mphamvu yoletsa ma virus kukhala yofanana, koma yamphamvu kuposa aciclovir, yokhala ndi zoletsa zamphamvu kwambiri pa cytomegalovirus yokhudzana ndi odwala Edzi.Amagwiritsidwa ntchito pochiza gawo lothandizira komanso gawo lokonzekera kwa odwala omwe ali ndi immunocompromised (kuphatikiza odwala AIDS) omwe ali ndi cytomegalovirus retinitis.Angagwiritsidwenso ntchito kupewa cytomegalovirus matenda odwala kulandira limba kupatsidwa zina kapena odwala AIDS ndi zotsatira zabwino cytomegalovirus serology mayeso.

Ganciclovir (CAS 82410-32-0) ndi yothandiza kwambiri, yotsika kawopsedwe komanso yosankha ma virus inhibitor yopangidwa ndi Syntex Company (United States).Ndi mankhwala oyamba omwe avomerezedwa ndi US FDA pochiza matenda a cytomegalovirus (CMV).Syntex yapatsidwa ufulu wokhawokha wopanga.Mu June 1988, piritsi limeneli linavomerezedwa kwa nthawi yoyamba kuti lilembedwe ku UK, kenako kuvomerezedwa motsatizana ndi France, United States, Japan, ndi West Germany, Italy ndi Canada ndi mayiko ena.Mpaka kumapeto kwa June 1999, izo zavomerezedwa m'mayiko oposa 70 ndi zigawo kupewa immunodeficiency odwala ndi cytomegalovirus matenda odwala limba kupatsidwa zina.Mu 2002, mapiritsi a Ganciclovir adavomerezedwa ndi FDA, akupezeka pano.