Gliepiride CAS 93479-97-1 Assay 98.0%~102.0% API Factory High Purity
Perekani ndi Kuyera Kwambiri ndi Ubwino Wokhazikika
Dzina la mankhwala: Glimepiride
CAS: 93479-97-1
Glimepiride pochiza matenda a shuga a mellitus osadalira insulini
API High Quality, Commercial Production
Dzina la Chemical | Glimepiride |
Mawu ofanana ndi mawu | Amaryl |
Nambala ya CAS | 93479-97-1 |
Nambala ya CAT | RF-API24 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | Chithunzi cha C24H34N4O5S |
Kulemera kwa Maselo | 490.62 |
Melting Point | 212.2 ~ 214.5 ℃ |
Mkhalidwe Wotumiza | Pansi pa Kutentha kwa Ambient |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera kapena Pafupifupi Woyera |
Chizindikiritso | IR (Yofanana ndi Standard) |
Zogwirizana nazo | |
Cis-Isomer (A) | ≤0.80% |
Sulfonamide (B) | ≤0.40% |
Urethane (C) | ≤0.10% |
3-Isomer (D) | ≤0.20% |
Chidetso China Chilichonse | ≤0.10% |
Zonse Zonyansa | ≤0.50% |
Kutaya pa Kuyanika | ≤0.50% |
Zotsalira pa Ignition | ≤0.10% |
Zitsulo Zolemera | ≤0.001% |
Kuyesa | 98.0% ~ 102.0% |
Test Standard | European Pharmacopeia (EP);United States Pharmacopoeia (USP) |
Kugwiritsa ntchito | Active Pharmaceutical Ingredient (API) |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga komanso ogulitsa Glimipiride (CAS: 93479-97-1) yokhala ndi mankhwala apamwamba kwambiri, omwe amagwira ntchito popanga mankhwala (API).Glimepiride ndi mankhwala ochepetsa shuga omwe amathandizira kuwongolera kuchuluka kwa shuga m'magazi.Glimepiride ndi yanthawi yayitali, ya m'badwo wachitatu wa sulfonylurea wokhala ndi zochita za hypoglycemic.
Glimepiride (dzina loyambirira la malonda Amaryl) ndi mankhwala omwe amapezeka m'kamwa a sulfonylurea antidiabetic.Monga ma sulfonylureas onse, glimepiride imagwira ntchito ngati secretagogue ya insulin.Amachepetsa shuga m'magazi polimbikitsa kutulutsidwa kwa insulin kuchokera ku maselo a pancreatic beta komanso powonjezera chidwi cha minofu yotumphukira ku insulin.Glimepiride mwina imamangiriza ku ma ATP-sensitive potassium channel receptors pa pancreatic cell, kumachepetsa kayendesedwe ka potaziyamu ndikupangitsa kuti nembanemba iwonongeke.Kuwonongeka kwa Membrane kumapangitsa kuti calcium ion ichuluke kudzera mu njira za calcium zomwe zimakhudzidwa ndi magetsi.Kuwonjezeka kwa ma ion calcium mu intracellular kumapangitsa kuti insulin ipangidwe.Glimepiride imagwiritsidwa ntchito makamaka pochiza odwala omwe ali ndi matenda amtundu wa 2 ndipo imatha kuchepetsa mwayi woti munthu azitha kukhala ndi zovuta zamtundu wa 2 shuga.Mankhwalawa adavomerezedwa ndi FDA mu 1995 ndipo amapangidwa ndi Sanofi-Aventis.Itha kugwiritsidwa ntchito limodzi ndi zakudya zoyenera komanso masewera olimbitsa thupi ndipo ingagwiritsidwenso ntchito yokha kapena ndi mankhwala ena oletsa shuga ngati pakufunika.Glimepiride itha kugwiritsidwa ntchito ngati monotherapy kapena kuphatikiza ndi insulin.