H-Gly-OMe·HCl CAS 5680-79-5 Glycine Methyl Ester Hydrochloride Assay >99.0%

1. Katundu: Izi ziyenera kukhala zoyera crystalline ufa.
2. Kuyesa:
1) Kutsimikiza kwa Glycine Methyl Ester Hydrochloride assay
1.1 Njira
Pansi pa acidic, chitsanzocho chimakhudzidwa ndi kuchuluka kwa siliva nitrate, ndipo siliva nitrate yochulukirapo imasinthidwanso ndi ammonium thiocyanate, kutanthauza ammonium ferric sulfate.
Monga chizindikiro, okwana klorini zili anatsimikiza molingana ndi buku la muyezo njira ankadya, ndi okwana klorini okhutira anachotsa zili glycine hydrochloride kupeza Glycine Methyl Ester Hydrochloride okhutira.
1.2 Reagents
Dibutyl phthalate;
Nitric acid solution: 2+3;
Silver nitrate muyezo wa titration solution: c(AgNO3) = 0.1 mol/L
Ammonium thiocyanate muyezo wa titration solution: c(NH4SCN) = 0.1 mol/L
Ammonium ferric sulfate (III) chizindikiro madzi: 80 g/L
1.3 Ndondomeko Yowunika
Kulemera pafupifupi 0.5g chitsanzo, molondola kwa 0.0001g.Ikani mu botolo la 250ml conical, sungunulani m'madzi 40ml, onjezerani 10 ml nitric acid solution, Add (50 ± 0.02) mL silver nitrate standard titration solution, 3mL ammonium ferric sulfate indicator solution, 4mL dibutyl phthalate, ndi thiocyanate solution ya thiocyanate titrated mpaka njira yothetsera kuwala bulauni ndipo anakhala colorless kwa 30 s.
1.4 Kuwerengera zotsatira
Gawo lalikulu la glycine methyl ester hydrochloric acid content w1, lomwe limawonetsedwa ngati%, limawerengedwa molingana ndi Equation (1):
w1= (c1V1-c2V2)*M/1000/m * 100-w2 *1.126 chilinganizo (1)
Kumene:
V1: Voliyumu ya silver nitrate standard titration solution (ml)
V2: Volume ya ammonium thiocyanate muyezo wa titration solution wodyedwa ndi titration (ml)
c1: Mtengo weniweni wa siliva nitrate muyezo wa titration solution (mol/L)
c2: Mtengo weniweni wa ammonium thiocyanate muyezo wa titration solution (mol/L)
w2: Kagawo kakang'ono (%) ka glycine hydrochloride zomwe zatsimikiziridwa mu Gawo 4.2
M: Molar kulemera kwa glycine methyl ester hydrochloride (g/mol)
1.126: Kusintha kokwanira kwa glycine hydrochloride kukhala Glycine methyl ester hydrochloride.
Chiwerengero cha masamu a zotsatira za miyeso iwiri yofananira chinatengedwa ngati zotsatira zoyezera, ndipo kusiyana kwakukulu pakati pa zotsatira ziwiri zofanana zoyezera sikunapitirire 0.05%.
2) Kutsimikiza kwa glycine hydrochloride
2.1 Njira
Pogwiritsa ntchito dimethyl yellow ngati chizindikiro, chitsanzocho chidasinthidwa ndi sodium hydroxide standard titrating solution, ndipo kuchuluka kwa yankho kunasinthidwa molingana ndi kumwa kwa sodium hydroxide standard.
Werengani glycine hydrochloride zomwe zili.
2.2 Reagent
Standard titration solution ya sodium hydroxide: c (NaOH) = 0.1mol/L
Dimethyl yellow chosonyeza madzi: 10 g/L
2.3 Ndondomeko Yowunika
Yezerani pafupifupi 5.0 g chitsanzo cha labotale, cholondola mpaka 0.0001g, mu beaker 200 ml, sungunulani ndi madzi 50ml, ndikuwonjezera madontho asanu a dimethyl.
Yellow chizindikiro madzi, ndi sodium hydroxide muyezo titration yankho titration mpaka yankho kuchokera wofiira lalanje chikasu ndi mapeto mfundo.
2.4 Kuwerengera zotsatira
Gawo lalikulu la w2 la glycine hydrochloride limawonetsedwa ngati % ndikuwerengedwa molingana ndi equation (2):
w2 =(V/1000)cM/m *100 chilinganizo (2)
Kumene:
V: Kuchuluka kwa sodium hydroxide standard titration solution (mL)
c: Mtengo weniweni wa sodium hydroxide standard titration solution (mol/L)
M: Molar kulemera kwa glycine hydrochloride (g/mol)
m: Kuchuluka kwachitsanzo (g)
Kutanthawuza kwa masamu a zotsatira za miyeso iwiri yofananira kunatengedwa ngati zotsatira za muyeso, ndipo kusiyana kotheratu pakati pa zotsatira za miyeso iwiri yofananira sikunapitirire 0.05%
3. Malo osungunula: Malingana ndi njira yodziwira malo osungunuka (Chinese Pharmacopoeia 2010 Appendix VIC), malo osungunuka ndi 172-178 ºC.
4. Kuyanika kuwonda: tengani mankhwalawa pa 105.0 ℃ ndikuwumitsa mpaka kulemera kosalekeza.Kutaya thupi sikuyenera kupitirira 0.5%.
5. Kusungirako: Izi ziyenera kusungidwa mufiriji kutali ndi kuwala.