Ibrutinib Deacryloylpiperidine CAS 330786-24-8 Purity>99.0% (HPLC)
Dzina la Chemical | 3-(4-Phenoxyphenyl) -1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Mawu ofanana ndi mawu | Ibrutinib wapakatikati N-2;Ibrutinib Deacryloylpiperidine;Chidetso cha Ibrutinib 8;5-(4-Phenoxyphenyl) -7H-pyrrolo[2,3-d]pyrimidin-4-ylamine;IBT4A;Ibrutinib N-Despiperidinyl Kusayera |
Nambala ya CAS | 330786-24-8 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | Chithunzi cha C17H13N5O |
Kulemera kwa Maselo | 303.32 |
Melting Point | > 262 ℃ (Dec.) |
Kuchulukana | 1.380±0.06 g/cm3 |
Kalasi Yowopsa | 6.1;Poizoni |
Packing Group | III |
COA & MSDS | Likupezeka |
Chiyambi | Shanghai, China |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Off-White to Khaki Powder |
Chizindikiritso | HNMR, LC-MS |
Kuyera / Kusanthula Njira | >99.0% (HPLC) |
Kutaya pa Kuyanika | <1.00% |
Single Max.Chidetso | <1.00% |
Zonse Zonyansa | <1.00% |
Zitsulo Zolemera (monga Pb) | <20ppm |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Pakati pa Ibrutinib (CAS: 936563-96-1) |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.
3-(4-Phenoxyphenyl) -1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS: 330786-24-8) ndi yothandiza yopangira pakati pa kaphatikizidwe ka Ibrutinib (CAS: 936563-96-1) ).Ibrutinib ndi mtundu wa Bruton tyrosine kinase (BTK) inhibitor, ukhoza kugwiritsidwa ntchito pochiza matenda a lymphocytic leukemia (CLL) ndi mantle cell lymphoma (MCL).MCL ndi CLL ndi a B-cell non-Hodgkin's lymphoma, omwe ndi ovuta kuchiza komanso osavuta kubwereza.Ma immunotherapy wamba alibe cholinga, nthawi zambiri amapezeka 3 kapena 4 zoyipa.Ibrutinib ndi B lymphocytes akhoza kulunjika ndi BTK yomwe ili yofunikira pakupanga, kusiyanitsa, ndi kufalitsa chidziwitso, kuletsa ntchito ya BTK mosasinthika, ndikuletsa kuchulukana kwa maselo otupa ndi kupulumuka bwino.Ibrutinib imatha kuyamwa mwachangu pambuyo pa makonzedwe amkamwa, pakadutsa 1 ~ 2h kufika pamlingo waukulu wamagazi, zotsatira zoyipa zimakhala za m'modzi kapena awiri, chifukwa chake, Ibrutinib idzakhala chisankho chatsopano chamankhwala a CLL ndi MCL.