N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

Kufotokozera Kwachidule:

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine

CAS: 152460-09-8

Maonekedwe: Ufa Wachikasu Kapena Wapafupi Wachikasu

Kuyera: ≥98.0% (HPLC)

Pakati pa Imatinib Mesylate (CAS: 220127-57-1) pochiza Philadelphia Chromosome-Positive Chronic Myeloid Leukemia (Ph + CML)

Ubwino Wapamwamba, Kupanga Zamalonda

Inquiry: alvin@ruifuchem.com


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Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Chemical Properties:

Dzina la Chemical N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
Mawu ofanana ndi mawu Imatinib Mesylate Pakati;2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine
Nambala ya CAS 152460-09-8
Nambala ya CAT RF-PI228
Stock Status Mu Stock, Kupanga Kukula Mpaka Matani
Molecular Formula C16H13N5O2
Kulemera kwa Maselo 307.31
Melting Point 188.0 ~ 193.0 ℃
Mtundu Ruifu Chemical

Zofotokozera:

Kanthu Zofotokozera
Maonekedwe Ufa Wachikasu Kapena Wapafupi Wachikasu
Chiyero ≥98.0% (HPLC)
Chinyezi (KF) ≤0.50%
Zonse Zonyansa ≤2.0%
Kusayera Kwambiri Kumodzi ≤1.0%
Zotsalira pakuyatsa ≤0.50%
Zitsulo Zolemera ≤20ppm
Test Standard Enterprise Standard
Kugwiritsa ntchito Pakati pa Imatinib Mesylate (CAS: 220127-57-1)

Phukusi & Kusunga:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.

Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.

Ubwino:

1

FAQ:

Ntchito:

Shanghai Ruifu Chemical Co., Ltd. ndiwopanga komanso ogulitsa N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine (CAS: 152460-09-8) ndi apamwamba.Ndiwopakatikati mwa kaphatikizidwe ka Imatinib Mesylate (CAS: 220127-57-1).
Imatinib Mesylate ndi kamolekyu kakang'ono kamene kamalepheretsa c-Abl protein-tyrosine kinase, Kwambiri makamaka kwa BCR-ABL, puloteni yokhudzana ndi matenda a myelogenous leukemia (CML) ndi mitundu ina ya acute lymphoblastic leukemia (ALL).Chochitika chosinthira pakati pa ma chromosome 9 ndi 22 chimapanga chromosome ya Philadelphia, yomwe imatulutsa puloteni ya Bcr-Abl fusion yokhala ndi ntchito ya aberrant kinase yomwe imalimbikitsa kuchuluka kwa maselo mwachangu.Imatinib Mesylate imamanga kinase yofunikayi, kuyimitsa kukula kokhudzana ndi CML.Imatinib Mesylate yawonetsedwanso kuti inhibit PDGFR ndi tyrosine kinases yokhudzana ndi c-Kit.Mapangidwe okhala ndi Imatinib Mesylate akhala akugwiritsidwa ntchito pochiza makhansa osiyanasiyana.

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