Irbesartan Intermediate Side Chain Hydrochloride CAS 151257-01-1 Purity>99.0% (HPLC) Factory
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Dzina la Chemical | 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride |
Mawu ofanana ndi mawu | Irbesartan Side Chain Hydrochloride;Kusayera kwa Irbesartan Lactam;Kusayera kwa Irbesartan A;2-Butyl-4-spirocyclopentane-2-imidazolin-5-one Hydrochloride;2-Butyl-1,3-diaza-spiro[4.4]non-1-en-4-one HCl |
Nambala ya CAS | 151257-01-1 |
Nambala ya CAT | Mtengo wa RF-PI1894 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C11H18N2O·HCl |
Kulemera kwa Maselo | 230.74 |
Kusungunuka mu Madzi | Zosungunuka mu Madzi |
Melting Point | 235.0 ~ 240.0 ℃ |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera mpaka Pafupifupi Woyera |
Kuyera / Kusanthula Njira | >99.0% (HPLC) |
Kutaya pa Kuyanika | <0.50% |
Zotsalira pa Ignition | <0.20% |
Zonse Zonyansa | <1.00% |
Proton NMR Spectrum | Zimagwirizana ndi Kapangidwe |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Wapakatikati wa Irbesartan (CAS: 138402-11-6) |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride (CAS: 151257-01-1), yomwe imadziwikanso kuti Irbesartan Side Chain Hydrochloride, ndi Intermediate ya Irbesartan (Avapro) (CAS Chithunzi: 138402-11-6).Irbesartan ndi angiotensin II receptor inhibitor, angiotensin II receptors amagawidwa mu AT1, AT2, irbesartan imatha kuletsa AngⅠtransform kukhala AngII mwa kusankha kutsekereza cholandilira cha AT1 cha AngII, makamaka kutsutsa angiotensin yotembenuza enzyme 1 receptor (AT500), AT500 ndi antagonism. Nthawi zambiri kuposa ya AT2, imatha kuletsa vasoconstriction ndi aldosterone kutulutsidwa mwa kusankha kutsekereza kumangiriza kwa AngII ndi AT1 cholandilira ndikupangitsa mphamvu ya antihypertensive.Izi sizimalepheretsa angiotensin kutembenuza enzyme (ACE), renin, ndi zolandilira mahomoni ena, komanso kupondereza dongosolo la kuthamanga kwa magazi komanso kusanja kwa njira za sodium ion.Irbesartan imathanso kuchepetsa kukonzanso kwa magetsi a myocardium, potero kuchepetsa kufa kwa odwala omwe ali ndi matenda oopsa, ndiye mankhwala othandiza kwambiri pochiza matenda oopsa komanso matenda amtima.