L-Cysteine ​​Hydrochloride Monohydrate CAS 7048-04-6 Assay 98.5~101.0% (Titration on Dried Basis) Factory

L-Cysteine ​​Hydrochloride Monohydrate (CAS: 7048-04-6) Njira Yoyesera ya AJI97
Chizindikiritso: Fananizani kuchuluka kwa mayamwidwe a infrared a chitsanzo ndi njira ya potaziyamu bromide disc.
Kuzungulira Kwapadera [α]D20: Zitsanzo zouma, C=8, 1mol/L HCl
State of Solution (Transmittance): 1.0g mu 10ml ya H2O, spectrophotometer, 430nm, 10mm cell makulidwe.
Kloridi (Cl): 350mg, B-2
Ammonium (NH4): A-1
Sulfate (SO4): 1.2g, (1), ref: 0.50ml ya 0.005mol/L H2SO4
Chitsulo (Fe): 1.5g, ref: 1.5ml ya Iron Std.(0.01mg/ml)
Zitsulo Zolemera (Pb): 2.0g, (1), pH = 7, ref: 2.0ml ya Pb Std.(0.01mg/ml)
Arsenic (As2O3): 2.0g, (1), ref: 2.0ml ya As2O3 Std.
Ma Amino Acids Ena: Chitsanzo Choyesera: 50μg, B-6-a, kulamulira;L-Cys·HCl·H2O 0.25μg
Kutaya pa Kuyanika: Mu vacuum, P2O5, kutentha kwa maola 20.
Zotsalira pa Ignition (Sulfated): AJI Test 13
Kuyesa: Zitsanzo zouma, 250mg, 0.05mol/L I2 1ml=15.762mg C3H7NO2S·HCl
Mayeso a pH: 1.0g mu 100ml ya H2O

L-Cysteine ​​Hydrochloride Monohydrate (CAS: 7048-04-6) USP35 Njira Yoyesera
TANTHAUZO
Cysteine ​​Hydrochloride ndi L-Cysteine ​​Hydrochloride Monohydrate ndipo ili ndi NLT 98.5% ndi NMT 101.5% ya L-Cysteine ​​Hydrochloride (C3H7NO2S·HCl), yowerengedwa pa zouma.
CHIZINDIKIRO
A. KUYAMBIRA KWA INFRARED <197K>
ZOYESA
NTCHITO
Chitsanzo: 250 mg ya Cysteine ​​Hydrochloride
Chopanda kanthu: Pitirizani monga momwe mwanenera mu Kusanthula popanda Chitsanzo.
Titrimetric system
(Onani Titrimetry <541>)
Mawonekedwe: Matchulidwe otsalira
Titrant: 0.1 N ayodini VS
Kubwerera kumbuyo: 0.1 N sodium thiosulfate VS
Kuzindikira komaliza: Zowoneka
Kusanthula: Tumizani Chitsanzo ku botolo la ayodini.Onjezerani 20.0 mL wa madzi ndi 4 g wa potaziyamu iodide, ndikusakaniza.Kuziziritsa yankho mu madzi oundana, ndipo onjezerani 5 mL wa 3 N hydrochloric acid ndi 25.0 mL wa 0.1 N ayodini VS.Ikani choyimitsa, ndipo mulole kuti muyime mumdima kwa 20 min.Titrate wowonjezera ayodini ndi Back titrant.Onjezani 3 mL ya nyenyezi ch TS pamene mapeto akuyandikira.Pa mawonekedwe a Blank determination.Werengerani kuchuluka kwa cysteine ​​hydrochloride (C3H7NO2S·HCl) mu Zitsanzo zomwe zatengedwa:
Zotsatira = {[(VB − VS) × N × F]/W} × 100
VB = Voliyumu yobwerera kumbuyo yomwe imadyedwa ndi Chopanda kanthu (mL)
VS = Voliyumu yobwerera kumbuyo yomwe imadyedwa ndi Zitsanzo (mL)
N = chikhalidwe chenicheni cha Back titrant (mEq/mL)
F= chinthu chofanana, 157.6 mg/mEq
W = kulemera kwachitsanzo (mg)
Njira zolandirira: 98.5% ~ 101.5% pazowuma
ZOCHITSA
ZOKHALA PA KUYATSA <281>: NMT 0.4%
CHLORIDE NDI SULFATE, Sulfate <221>
Njira yothetsera: 0,10 mL ya 0.020 N sulfuric acid
Chitsanzo: 0.33 g ya Cysteine ​​Hydrochloride
Njira zolandirira: NMT 0.03%
IRON <241>: NMT 30ppm
ZINTHU ZONSE, Njira I <231>: NMT 15ppm
ZOKHUDZANA NDI COMPOUNDS
N-Ethylmaleimide solution: 40 mg/mL ya N-ethylmaleimide mu mowa
Sungunulani 20 mg ya USP L-Cysteine ​​Hydrochloride RS mu 10.0 ml ya madzi.Onjezani 10.0 ml ya yankho la N-Ethylmaleimide, ndikusakaniza.Lolani kuti yankho liyime kwa mphindi 5 musanagwiritse ntchito.
Njira yothetsera: 0.05 mg/mL kuchokera ku Standard stock solution m'madzi.[ ZOYENERA - Yankho ili lili ndi ndende yofanana ndi 0.5% ya yankho la Zitsanzo.]
Njira yothetsera kuyenerera: Kusamutsa 10 mg ya USP L-Tyrosine RS ndi 10 mL ya Standard stock solution ku 25-mL voliyumu botolo.Dilute ndi madzi kuti voliyumu.
Zitsanzo za yankho la stock: Chotsani 0.2 g wa Cysteine ​​Hydrochloride ku botolo la volumetric 10-mL, sungunulani, ndi kusungunula ndi madzi mpaka kuchuluka.
Yankho lachitsanzo: Ku 5.0 mL ya Sample stock solution onjezerani 5.0 mL ya N-Ethylmaleimide solution, ndi kusakaniza.Lolani kuti yankho liyime kwa mphindi 5 musanagwiritse ntchito.
Chromatographic system (Onani Chromatography <621>, Thin-Layer Chromatography.)
Njira: TLC
Adsorbent: 0.25-mm wosanjikiza wa chromatographic silica gel osakaniza
Kuchuluka kwa ntchito: 5μL
Kupanga zosungunulira: Mowa wa Butyl, glacial acetic acid, ndi madzi (3:1:1)
Utsi wopopera: 2 mg/mL wa ninhydrin wosakaniza wa mowa wa butyl ndi 2N acetic acid (95:5)
Kuyenerera kwadongosolo
Zofunika pazabwino: Chromatogram ya njira yothetsera kukwanira kwa System imawonetsa mawanga awiri olekanitsidwa bwino.
Kusanthula
Zitsanzo: Yankho lokhazikika, yankho loyenera dongosolo, ndi yankho lachitsanzo.
Mukayanika mbaleyo, pukutani ndi Spray reagent, ndi kutentha pakati pa 100 ° ndi 105 ° kwa mphindi 15.Yang'anani mbaleyo pansi pa kuwala koyera.
Njira zolandirira: Malo aliwonse achiwiri a Sample solution si aakulu kapena okulirapo kuposa malo oyambira a Standard solution.
Zonyansa zapayekha: NMT 0.5%
Zonyansa zonse: NMT 2.0%
MAYESO AKE
KUSINTHA KWA MASO, Kuzungulira Kwachindunji <781S>
Yankho lachitsanzo: 80 mg/mL mu 6 N hydrochloric acid
Zovomerezeka zovomerezeka: + 5.7 ° mpaka + 6.8 °
KUYANUKA KWA LOSSON <731>: Yanikani chitsanzo pa kutentha kwa chipinda pazitsulo zosapitirira 5 mm za mer cury kwa 24 h: imataya 8.0% ~ 12.0% ya kulemera kwake.
ZOWONJEZERA ZOFUNIKA
KUPAKA NDI KUSEKA: Sungani m’zotengera zotsekedwa bwino.
MFUNDO ZA USP REFERENCE <11>
USP L-Cysteine ​​Hydrochloride RS
USP L-Tyrosine RS