LCZ696 Yapakatikati CAS 1426129-50-1 Chiyero ≥98.0% (HPLC) ee ≥99.0% Factory High Purity
Zogulitsa Zamalonda LCZ696 (CAS: 936623-90-4) Zapakati Zofananira:
(R) -tert-Butyl (1-([1,1-biphenyl] -4-yl)-3-hydroxypropan-2-yl)carbamate CAS: 1426129-50-1
(R,E) -5-(1,1'-biphenyl-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid CAS: 1012341-48-8
(2R,4S)-5-(1,1'-biphenyl-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid CAS: 1012341-50-2
(2R,4S) -ethyl 5-(1,1'-biphenyl-4-yl)-4-amino-2-methylpentanoate HCl CAS: 149690-12-0
AHU-377 (mchere wa hemicalcium) CAS: 1369773-39-6
AHU-377;Sacubitril CAS: 149709-62-6
Mtengo wa LCZ696;Entresto;Kusakaniza kwa Sacubitril ndi Valsartan CAS: 936623-90-4
| Dzina la Chemical | (R) -tert-Butyl (1-([1,1-biphenyl] -4-yl) -3-hydroxypropan-2-yl)carbamate |
| Mawu ofanana ndi mawu | Mtengo wa LCZ696 |
| Nambala ya CAS | 1426129-50-1 |
| Nambala ya CAT | Chithunzi cha RF-PI169 |
| Stock Status | Mu Stock, Kupanga Kukula Mpaka Mazana a Kilogram |
| Molecular Formula | C20H25NO3 |
| Kulemera kwa Maselo | 327.42 |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Woyera mpaka Woyera |
| Kuyera / Kusanthula Njira | ≥98.0% (HPLC) |
| Enantiomeric Zowonjezera | ≥99.0% |
| Chinyezi (KF) | ≤1.0% |
| Zogwirizana ndi A | ≤1.0% (RRT=0.5) A=(R)-3-([1,1'-biphenyl]-4-yl)-2-aminopropan-1-ol |
| Zogwirizana ndi B | ≤1.0% (RRT=0.85) B=Triphenylphosphine oxide |
| Zinthu Zina | ≤1.0% |
| Zonse Zonyansa | ≤2.0% |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | Pakati pa LCZ696 (CAS: 936623-90-4) pochiza HFrEF |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Wopanga ndi Kuyera Kwambiri ndi Ubwino Wokhazikika
Zogulitsa Zamalonda LCZ696 (CAS: 936623-90-4) Zapakati Zofananira:
(R) -tert-Butyl (1-([1,1-biphenyl] -4-yl)-3-hydroxypropan-2-yl)carbamate CAS: 1426129-50-1
(R,E) -5-(1,1'-biphenyl-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid CAS: 1012341-48-8
(2R,4S)-5-(1,1'-biphenyl-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid CAS: 1012341-50-2
(2R,4S) -ethyl 5-(1,1'-biphenyl-4-yl)-4-amino-2-methylpentanoate HCl CAS: 149690-12-0
AHU-377 (mchere wa hemicalcium) CAS: 1369773-39-6
AHU-377;Sacubitril CAS: 149709-62-6
Mtengo wa LCZ696;Entresto;Kusakaniza kwa Sacubitril ndi Valsartan CAS: 936623-90-4
LCZ696 ndi mankhwala oyesera omwe amapangidwa ndi Novartis Pharmaceutical ya ku United States pofuna kuchiza odwala omwe ali ndi Kulephera kwa Mtima ndi Kuchepa kwa Ejection Fraction (HFrEF).Kulephera kwa mtima ndi matenda oopsa.Mtima wa wodwalayo sungathe kupopa magazi okwanira kuti apereke thupi, ndikuwoneka zizindikiro za dyspnea, kutopa ndi kusunga madzimadzi pang'onopang'ono, kenako pang'onopang'ono kuwonjezeka, zimakhudza kwambiri moyo.LCZ696 imatha kupititsa patsogolo chitetezo chathupi chamthupi motsutsana ndi kulephera kwa mtima, komanso kukulitsa kuchuluka kwa ma peptides a natriuretic ndi ma peptides ena amkati a vasoactive, ndikuletsa dongosolo la renin-angiotensin-aldosterone (RAAS).LCZ696 yaphatikizana ndi Novartis's Hypertension Medication (Diovan, generic name: valsartan) ndi mankhwala oyesera AHU-377.AHU377 imatchinga makina a peptides awiri omwe amachepetsa kuthamanga kwa magazi.Diovan imathandizira vasodilatation ndikupangitsa thupi kutulutsa sodium ndi madzi.
