Lenvatinib Mesylate Intermediate CAS 205448-65-3 Purity>98.0% (HPLC) Factory

Kufotokozera Kwachidule:

Dzina la Mankhwala: Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate

CAS: 205448-65-3

Kuyera: > 98.0% (HPLC)

Maonekedwe: Woyera-Woyera mpaka Ufa Wachikasu

Pakati pa Lenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com

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Kufotokozera:

Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Ndi Kuyera Kwambiri
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Chemical Properties:

Dzina la Chemical	Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate
Mawu ofanana ndi mawu	1,4-Dihydro-7-Methoxy-4-Oxo-6-Quinolinecarboxylic Acid Methyl Ester;7-Methoxy-4-Oxo-1,4-Dihydro-Quinoline-6-Carboxylic Acid Methyl Ester;Lenvatinib Wapakati 3
Nambala ya CAS	205448-65-3
Nambala ya CAT	Chithunzi cha RF-PI1973
Stock Status	Mu Stock, Mphamvu Yopanga 50 MT / Chaka
Molecular Formula	C12H11NO4
Kulemera kwa Maselo	233.22
Boiling Point	421.0±45.0℃
Kuchulukana	1.267±0.060 g/cm3
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Ufa Woyera mpaka Wachikasu
Kuyera / Kusanthula Njira	>98.0% (HPLC)
Kutaya pa Kuyanika	<1.00%
Zotsalira pa Ignition	<0.50%
Zonse Zonyansa	<2.00%
H-NMR	Zimagwirizana ndi Kapangidwe
Test Standard	Enterprise Standard
Kugwiritsa ntchito	Pharmaceutical Intermediates

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi

Ubwino:

FAQ:

Ntchito:

Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate (CAS: 205448-65-3) ndi yapakatikati ya Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib, yogulitsidwa pansi pa dzina la Lenvima pakati pa ena, ndi mankhwala oletsa khansa pochiza mitundu ina ya khansa ya chithokomiro komanso makhansa ena.Inapangidwa ndi Eisai Co. ndipo imakhala ngati multiple kinase inhibitor motsutsana ndi VEGFR1, VEGFR2 ndi VEGFR3 kinases.Lenvatinib imavomerezedwa (kuyambira 2015) pochiza khansa ya chithokomiro yosiyana yomwe imakhala yobwerezabwereza kapena ya metastatic, yopita patsogolo, ndipo sanayankhe chithandizo cha radioactive ayodini (radioiodine).Mu Meyi 2016, bungwe la US Food and Drug Administration (FDA) lidavomereza (mophatikiza ndi everolimus) kuti azichiza matenda amtundu wa renal cell carcinoma kutsatira chithandizo chimodzi choyambirira cha anti-angiogenic.Mankhwalawa amavomerezedwanso ku US ndi ku European Union kwa hepatocellular carcinoma yomwe singathe kuchotsedwa opaleshoni kwa odwala omwe sanalandire chithandizo cha khansa pakamwa kapena jekeseni.