Letrozole CAS 112809-51-5 API Factory Aromatase Inhibitor II High Quality
Perekani ndi Kuyera Kwambiri ndi Ubwino Wokhazikika
Dzina la Mankhwala: Letrozole
CAS: 112809-51-5
Aromatase Inhibitor II
API High Quality, Commercial Production
| Dzina la Chemical | Letrozole |
| Mawu ofanana ndi mawu | CGS-20267;Femara |
| Nambala ya CAS | 112809-51-5 |
| Nambala ya CAT | RF-API86 |
| Stock Status | Mu Stock, Kupanga Kufikira Mazana a Kilogram |
| Molecular Formula | C17H11N5 |
| Kulemera kwa Maselo | 285.3 |
| Melting Point | 181.0 mpaka 183.0 ℃ |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Wa Crystalline Woyera mpaka Woyera |
| Kusungunuka | Zosungunuka Momasuka mu Dichloromethane, Zosungunuka Pang'ono Mu Ethanol ndi Zosasungunuka M'madzi |
| Chizindikiro cha IR | Spectrum ya chitsanzo imafanana ndi ya reference standard |
| Chizindikiro cha HPLC | Nthawi yosungitsa yachiyeso imafanana ndi yanthawi yolozera |
| Mkati mwa Madzi (wolemba KF) | ≤0.30% |
| Zotsalira pa Ignition | ≤0.10% |
| Zogwirizana nazo | |
| Zogwirizana ndi A | ≤0.30% |
| Zogwirizana ndi B | ≤0.20% |
| Chidetso Chilichonse Chosadziwika | ≤0.10% |
| Zonyansa Zonse Zosadziwika | ≤0.30% |
| Zonse Zonyansa | ≤0.50% |
| Zosungunulira Zotsalira | |
| Ethyl Acetate | ≤0.50% |
| Methanol | ≤0.30% |
| Ethanol | ≤0.50% |
| DMF | ≤0.088% |
| Zitsulo Zolemera | ≤10ppm |
| Kuyesa | 98.0% ~ 102.0% (popanda madzi) |
| Shelf Life | Miyezi 24 |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | API, Aromatase Inhibitor II |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Letrozole (CAS 112809-51-5) ndi gawo la m'badwo watsopano wa aromatase inhibitors omwe amasankha kwambiri ndipo ndi opangidwa mwaluso opangidwa ndi benzotriazole.Letrozole imalepheretsa aromatase kuti achepetse misinkhu ya estrogen, motero amalepheretsa estrogen kuti asalimbikitse kukula kwa chotupa.Ntchito yake mu vivo ndi mphamvu 150-250 kuposa ya m'badwo woyamba aromatase inhibitor Amarante.Chifukwa chosankha kwambiri, sichidzakhudza glucocorticoid, mineralocorticoid ndi ntchito za chithokomiro;ngakhale pa mlingo waukulu, sizikhala ndi zotsatira zolepheretsa adrenal corticosteroid secretion, zomwe zimapatsa chiwerengero chachikulu cha mankhwala.Letrozole ilibe poizoni wobisika ku machitidwe aliwonse a thupi ndi ziwalo zomwe zikuyang'aniridwa, alibe mutagenicity ndi carcinogenic zotsatira, ali ndi zotsatira zochepa zapoizoni, amalekerera bwino, ndipo ali ndi zotsatira zamphamvu za anticancer kuposa ena aromatase inhibitors ndi antiestrogen mankhwala.Letrozole ndi yoyenera kwa odwala khansa ya m'mawere apamwamba omwe sanayankhepo chithandizo cha estrogen-suppressing komanso chithandizo cha khansa ya m'mawere oyambirira.Amagwiritsidwa ntchito pochiza odwala omwe ali ndi khansa yapamwamba ya m'mawere ndipo amakhala ngati chithandizo chachiwiri kuti atsatire chithandizo cha antiestrogen chosapambana.
