Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26-8 Purity>99.0% (HPLC) Nintedanib Esylate Intermediate Factory
Shanghai Ruifu Chemical Co., Ltd. ndiwopanga komanso wogulitsa Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) yokhala ndiukadaulo wapamwamba kwambiri, wopanga malonda.
Dzina la Chemical | Methyl 2-Oxoindoline-6-Carboxylate |
Mawu ofanana ndi mawu | 2-Oxoindoline-6-Carboxylic Acid Methyl Ester;Methyl Oxindole-6-Carboxylate |
Nambala ya CAS | 14192-26-8 |
Nambala ya CAT | Chithunzi cha RF-PI1524 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C10H9NO3 |
Kulemera kwa Maselo | 191.19 |
Melting Point | 184.0 ~ 190.0 ℃ |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Wachikasu Wopepuka mpaka Wabulauni |
1 H NMR Spectrum | Zogwirizana ndi Kapangidwe |
Kuyera / Kusanthula Njira | >99.0% (HPLC) |
Kutaya pa Kuyanika | <1.00% |
Zonse Zonyansa | <1.00% |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Pakati pa Nintendodanib Esylate (CAS: 656247-18-6) |
Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) Njira Yopanga
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.
Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) ndi yapakatikati yomwe imagwiritsidwa ntchito pokonzekera Nintedanib Esylate (CAS: 656247-18-6).Nintedanib Esylate ndi amphamvu, oral triple angiokinase inhibitor yopangidwa ndi Boehringer Ingelheim yomwe imayang'ana njira za proangiogenic ndi pro-fibrotic zomwe zimalumikizidwa ndi vascular endothelial growth factor receptor, fibroblast growth factor receptor ndi plateletderived growth factor receptor mabanja, komanso Src ndi Flt-3. kinase.Nintedanib Esylate adavomerezedwa kuti azichiza matenda a idiopathic pulmonary fibrosis (IPF), momwe mapapu amakhala amabala pang'onopang'ono pakapita nthawi, ndi US FDA mu Okutobala 2014 ndi EMA mu Januware 2015. FDA idapereka nintedanib esylate mwachangu. , kuunikanso koyambirira, malonda a ana amasiye, ndi mayina opambana.Idavomerezedwanso ndi EMA mu Novembala 2014 pochiza khansa ya m'mapapo yosakhala yaying'ono kuphatikiza ndi docetaxel pambuyo pamankhwala oyamba a chemotherapy.