Molnupiravir (EIDD-2801) CAS 2349386-89-4 COVID-19 API High Quality
Zogulitsa Zamalonda za Molnupiravir ndi Othandizira Ogwirizana ndi Ubwino Wapamwamba
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Molnupiravir (EIDD-2801) CAS 2349386-89-4
| Dzina la Chemical | Molnupiravir (EIDD-2801) |
| Mawu ofanana ndi mawu | MK-4482;β-D-N4-Hydroxycytidine-5'-isopropyl ester;((2R,3S,4R,5R) -3,4-dihydroxy-5-((E)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2 -yl) methyl isobutyrate |
| Nambala ya CAS | 2349386-89-4 |
| Nambala ya CAT | RF-API97 |
| Stock Status | Mu Stock, Kupanga Kufikira Mazana a Kilogram |
| Molecular Formula | C13H19N3O7 |
| Kulemera kwa Maselo | 329.31 |
| Kusungunuka | Zosungunuka mu DMSO |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Woyera mpaka Woyera |
| Chizindikiro cha IR | Zitsanzo za Spectrum zimafanana ndi zomwe zili muyeso |
| Chizindikiro cha HPLC | Nthawi yosungira pachimake chachikulu chachitsanzo chachitsanzo chikufanana ndi yankho lokhazikika |
| Zogwirizana nazo | |
| Chidetso A | ≤0.15% |
| Chidetso B | ≤0.15% |
| Chidetso Chilichonse Chosadziwika | ≤0.15% |
| Zonyansa Zonse Zosadziwika | ≤0.30% |
| Zonse Zonyansa | ≤0.50% |
| Zosungunulira Zotsalira | |
| N-Heptane | ≤5000ppm |
| Ethanol | ≤5000ppm |
| Isopropyl Acetate | ≤5000ppm |
| Acetonitrile | ≤410ppm |
| Methylene Dichloride | ≤600ppm |
| Acetone | ≤5000ppm |
| Isopropanol | ≤5000ppm |
| M'madzi (KF) | ≤0.50% |
| Zotsalira pa Ignition | ≤0.10% |
| Kuzungulira kwa Optical | -7.5° mpaka -9.5° (C=0.5, Methanol) |
| Zitsulo Zolemera | ≤10ppm |
| Kuyera / Kusanthula Njira | ≥99.5% (230nm) |
| Njira Yoyesera / Kusanthula | 98.0% ~ 102.0% (HPLC pa zouma) |
| Shelf Life | Miyezi 24 |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | API, Molnupiravir (EIDD-2801) COVID-19 Inhibitor |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Molnupiravir (EIDD-2801, MK-4482) ndi mankhwala opangidwa pakamwa a ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) yokhala ndi antiviral yochulukirapo motsutsana ndi SARS-CoV-2, MERS-CoV, SARS-CoV, ndi woyambitsa wa COVID-19.Molnupiravir amagulitsidwa pansi pa dzina la Lagevrio ndipo nthawi zambiri amatchedwa emorivir.Molnupiravir yawonetsedwa kuti imathandizira kugwira ntchito kwa m'mapapo, kuchepetsa thupi komanso kuchepetsa kuchuluka kwa kachilomboka m'mapapo.Kuphatikiza pa zochitika zolimbana ndi ma coronavirus, Molnupiravir, mu maphunziro a labotale, yawonetsa zochitika zolimbana ndi fuluwenza ya nyengo ndi mbalame, kachilombo koyambitsa matenda a syncytial, kachilombo ka chikungunya, kachilombo ka Ebola, kachilombo ka Venezuelan equine encephalitis virus, ndi Eastern equine encephalitis virus.Molnupiravir poyambilira idapangidwa kuti izithandizira chimfine ku Emory University ndi kampani yopanga mankhwala yaku yunivesiteyo, Drug Innovation Ventures at Emory (DRIVE), koma akuti idasiyidwa chifukwa cha zovuta za mutagenicity.Kenako idagulidwa ndi kampani yaku Miami ya Ridgeback Biotherapeutics, yomwe pambuyo pake idagwirizana ndi Merck & Co.Molnupiravir idavomerezedwa kuti igwiritsidwe ntchito pachipatala ku United Kingdom mu Novembala 2021.
