N-Acetyl-L-Tyrosine CAS 537-55-3 (Ac-Tyr-OH; NALT) Chiyeso 99.0~101.0 Factory

N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) Njira Yoyesera ya AJI97
N-Acetyl-L-Tyrosine, ikauma, imakhala ndi osachepera 99.0 peresenti komanso osapitirira 101.0 peresenti ya N-Acetyl-L-Tyrosine (C11H13NO4).
Kufotokozera: Makhiristo oyera kapena ufa wa crystalline, kukoma kwa asidi kwambiri
Momasuka sungunuka m'madzi.
Kusungunuka (H2O, g/100g): 17.5 (20 ℃), 72.4 (40 ℃), 158 (60 ℃)
Chizindikiritso: Fananizani kuchuluka kwa mayamwidwe a infrared a chitsanzo ndi njira ya potaziyamu bromide disc.
Kuzungulira Kwapadera [α]20/D: Zitsanzo zouma, C=4, H2O
State of Solution (Transmittance): 0.5g mu 10ml ya H2O, spectrophotometer, 430nm, 10mm cell makulidwe.
Chloride (Cl): 0.7g, A-1, ref: 0.40ml ya 0.01mol/L HCl
Ammonium (NH4): B-1
Sulfate (SO4): 1.2g, (1), ref: 0.50ml ya 0.005mol/L H2SO4
Chitsulo (Fe): 0.5g, ref: 1.5ml ya Iron Std.(0.01mg/ml)
Zitsulo Zolemera (Pb): 2.0g, (3), ref: 2.0ml ya Pb Std.(0.01mg/ml)
Arsenic (As2O3): 1.0g, (1), ref: 2.0ml ya As2O3 Std.
Kutaya pa Kuyanika: pa 105 ℃ kwa maola atatu
Zotsalira pa Ignition (Sulfated): AJI Test 13
Kuyesa: Zitsanzo zouma, 300mg, (1), 40ml H2O, (2), 0.1mol/L NaOH, 1ml=22.323mg C11H13NO4
Tyrosine: Liquid chromatography.Mkhalidwe wogwira ntchito: Chowunikira: UV mayamwidwe photometer (214nm);Mzere: ODS, 4.6mm x 150mm;Kutentha kwa Mzere: Kutentha kwa chipinda.Kuthamanga kwapakati: 1ml / min;Gawo la m'manja: 0.04mol/L yankho la monopotassium phosphate (pH 4.35): Methanol (193:3)
pH: 1.25g mu 50ml ya H2O
Malire osungira ndi momwe amasungira: Zotengera zothina zosungidwa pamalo otenthetsera mchipinda chowongolera (zaka 2).

N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) Njira Yoyesera ya USP35
TANTHAUZO
N-Acetyltyrosine ili ndi NLT 98.5% ndi NMT 101.0% ya C11H13NO4, monga N-Acetyl-L-Tyrosine, yowerengedwa pa zouma.
CHIZINDIKIRO
A. KUYAMBIRA KWA INFRARED <197K>
B. KUSINTHA KWA MASO, Kusinthasintha Kwachindunji <781S>
Yankho lachitsanzo: 10 mg/mL
Njira zolandirira: NLT +46.0° ndi NMT +49.0°, zotsimikiziridwa pa 20°
C. Mtengo wa RF wa malo ofunikira a Sample solution pakuyesa kwa Organic Impurities ndi wofanana ndi wa Standard solution 1.
ZOYESA
NTCHITO
Yankho lachitsanzo: Sungunulani pafupifupi 180 mg ya N-Acetyltyrosine, yolemera, mu 50 ml ya madzi opanda carbon dioxide.
Titrimetric system
(Onani Titrimetry <541>)
Mode: Direct titration
Kukula: 0.1 N sodium hydroxide VS
Kuzindikira komaliza: Potentiometric
Kufanana: ML iliyonse ya 0.1 N sodium hydroxide VS ndi yofanana ndi 22.32 mg ya C11H13NO4.
ZOCHITSA
Zowonongeka Zachilengedwe
KUYATSA ZOKHALA <281>: NMT 0.1%
CHLORIDE NDI SULFATE, Chloride <221> NMT 200 ppm.Gawo la 0,7-g likuwonetsa chloride yochulukirapo kuposa 0.40 ml ya 0.01 N hydrochloric acid.
CHLORIDE NDI SULFATE, Sulfate <221> NMT 200 ppm.Gawo la 1.2-g limawonetsa sulphate yochulukirapo kuposa 0,25 ml ya 0.020 N sulfuric acid.
IRON <241>: NMT 20ppm
ZINTHU ZONSE, Njira I <231>: NMT 10ppm
Zowonongeka Zachilengedwe
NTCHITO
Adsorbent: 0.25-mm wosanjikiza wa chromatographic silica gel osakaniza
Standard stock solution 1: 8 mg/mL ya USP N-Acetyl-L-tyrosine RS mumsanganizo wa madzi, glacial acetic acid, ndi mowa (3:3:94)
Yankho lokhazikika 1: Dilute Standard stock solution 1 ndi mowa kuti mupeze yankho lodziwika bwino la 0.4 mg/mL
Standard njira 2: 0.8 mg/mL wa USP L-Tyrosine RS kusungunuka mu osakaniza glacial acetic asidi ndi madzi (1:1), ndi kuchepetsedwa ndi mowa
Yankho lachitsanzo: Chotsani 0,8 g wa N-Acetyltyrosine mu botolo la volumetric 10-mL, sungunulani mu 6 ml ya osakaniza a glacial acetic acid ndi madzi (1: 1), ndi kusungunula ndi mowa mpaka kuchuluka kwake.
Kuchuluka kwa ntchito: 5µL
Kupanga zosungunulira: Chisakanizo cha ammonia ndi 2-propanol (3:7)
Spray reagent: Sungunulani 0,2 g wa ninhydrin mu 100 ml ya osakaniza a butanol ndi 2 N acetic acid (95:5).
Kuyenerera kwadongosolo
Zofunika pazabwino: Chromatogram ya njira yothetsera kukwanira kwa System imawonetsa mawanga awiri olekanitsidwa bwino.
Kusanthula: Chitani monga momwe mwawuzira Chromatography <621> Thin-Layer Chromatography.Mutatha kuyanika mbale, bwerezani ndondomeko ya chitukuko.Mukayanikanso mpweya kachiwiri, pukutani ndi Spray reagent, ndi kutentha pakati pa 100 ° ndi 105 ° kwa mphindi 15.
Njira zolandirira: Malo aliwonse achiwiri a Yankho lachitsanzo sakhala okulirapo kapena okulirapo kuposa malo oyambira a Standard solution1, kupatula malo olingana ndi tyrosine, omwe siakuluakulu kapena olimba kuposa malo oyambira a Standard solution 2.
Zonyansa zapayekha: NMT 0.5%
Malire a tyrosine: NMT 1.0%
MAYESO AKE
KUYANUKA KWA LOSSON <731>: Yanikani chitsanzo pa 105℃ kwa 3 h: imataya NMT 0.1% ya kulemera kwake.
ZOWONJEZERA ZOFUNIKA
KUPAKA NDI KUSEKA: Sungani m’zotengera zotsekedwa bwino, ndipo sungani pamalo otenthetsera bwino m’chipinda.
MFUNDO ZA USP REFERENCE <11>
USP N-Acetyl-L-tyrosine RS
USP L-Tyrosine RS