N-Fluorobenzenesulfonimide (NFSI) CAS 133745-75-2 Purity >98.0% (HPLC) Fluorinating Reagent

N-Fluorobenzenesulfonimide (NFSI) (CAS: 133745-75-2), Versatile fluorinating reagent yomwe imagwiritsidwa ntchito mu fluorination ya aryls, enolates, carbanions, organolithiums, etc.
N-Fluorobenzenesulfonimide ndi electrophilic fluorinating agent mu organic synthesis kuti adziwitse fluorine mu mamolekyu osalowerera ndale.Amagwiritsidwanso ntchito ku fluorinate ma nucleophilic substrates monga reactive organometallic mitundu ndi malonate anions.NFS ikhoza kupangidwa ndi zomwe benzenesulfonimide ndi fluorine.
N-Fluorobenzenesulfonimide ndi chatsopano, chokhazikika komanso chofatsa cha fluorination reagent, chomwe chimatha kuyambitsa maatomu a fluorine mu carbonyl ortho malo a mamolekyu achilengedwe, ndipo amatha kuchitapo kanthu pamagetsi onunkhira a elekitironi, enol sila ne, ene Chemicalbook mowa lifiyamu mchere, etc. Panopa kafukufuku malo monga Nazarov cyclization anachita catalyzed ndi chitsulo kapena cobalt kupanga asanu mamembala mphete, ndi asymmetric catalysis wa enantioselective α-fluorination.
N-Fluorobenzenesulfonimide fluorinate aromatics, enolates, azaenolates ndi carbanions pa zokolola zambiri.Amagwiritsidwa ntchito pa diastereoselective fluorination ya Li enolates ya chiral carboximides, pakuwongolera fluorination ya ortho-lithiated aromatics ndikuwunikanso ma electrophilic NF fluorinating agents.Asymmteric fluorinations ikuchitika pamaso pa Pd-BINAP chothandizira dongosolo kutentha firiji mu madzi ayoni.Ndi reagent yomwe imagwiritsidwa ntchito mu palladium-catalyzed enantioselective fluorination ya t-butoxycarbonyl lactones ndi lactam.Amagwiritsidwanso ntchito mu electrophilic difluorination ya dihalopyridines ndi butyl lithiamu komanso kutembenuka mwachindunji kwa mowa kukhala dibenzenesulfonamides ndi triphenylphosphine.