N-Hydroxysuccinimide (HOSu) CAS 6066-82-6 Coupling Reagent Purity >99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6) yokhala ndipamwamba kwambiri.Ruifu Chemical imapereka ma reagents oteteza ndi ma reagents ophatikiza.Ruifu atha kubweretsa padziko lonse lapansi, mtengo wampikisano, zochepa komanso zochulukirapo zomwe zilipo.Gulani N-Hydroxysuccinimide,Please contact: alvin@ruifuchem.com
Dzina la Chemical | N-Hydroxysuccinimide |
Mawu ofanana ndi mawu | HOSu;NHS;1-Hydroxysuccinimide;1-Hydroxy-2,5-Pyrrolidinedione;N-Hydroxy-2,5-dioxopyrrolidine |
Stock Status | Mu Stock, Mass Production |
Nambala ya CAS | 6066-82-6 |
Molecular Formula | C4H5NO3 |
Kulemera kwa Maselo | 115.09 g / mol |
Melting Point | 93.0 ~ 98.0 ℃ (lit.) |
Kuchulukana | 1.649 |
Zomverera | Hygroscopic.Kutentha Kwambiri, Kusamva Chinyezi |
Kusungunuka mu Dioxane | Zosungunuka mu Dioxane, Pafupifupi Transparency |
Kusungunuka mu Madzi | Zosungunuka mu Madzi |
Kusungirako Temp. | Malo Ozizira & Owuma (2~8℃) |
COA & MSDS | Likupezeka |
Gulu | Coupling Reagents |
Mtundu | Ruifu Chemical |
Zinthu | Miyezo Yoyendera | Zotsatira |
Maonekedwe | White Crystalline Powder | Zimagwirizana |
Melting Point | 93.0 ~ 98.0 ℃ | 94.0 ~ 97.0 ℃ |
Kutaya pa Kuyanika | <0.50% | 0.15% |
Kuyera / Kusanthula Njira | >99.0% (HPLC) | 99.5% |
Infrared Spectrum | Zimagwirizana ndi Kapangidwe | Zimagwirizana |
Proton NMR Spectrum | Zimagwirizana ndi Kapangidwe | Zimagwirizana |
Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zanenedwa |
Gawo la mafoni: 0.1% yankho la phosphoric acid: acetonitrile =90:10
Kutalika: 220nm
Kuthamanga: 1ml / min
Phukusi:Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Kusamala chinyezi.Sungani m'mitsuko yomata pamalo ozizira komanso owuma (2~8 ℃) kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
Zizindikiro Zowopsa Xi - Zokwiyitsa
Zizindikiro Zowopsa
36/37/38 - Zokwiyitsa maso, kupuma komanso khungu.
Kufotokozera Zachitetezo
S22 - Osapumira fumbi.
S24/25 - Pewani kukhudzana ndi khungu ndi maso.
S26 - Mukakhudzana ndi maso, muzimutsuka nthawi yomweyo ndi madzi ambiri ndipo funsani malangizo achipatala.
S36 - Valani zovala zoyenera zodzitetezera.
WGK Germany 3
TSCA Inde
HS kodi 2925190090
Hazard Note Irritant
N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6), reagent yokonzekera esters yogwira amino acid.Peptide solid phase synthesis yolumikizira wothandizira.
N-Hydroxysuccinimide nthawi zambiri amagwiritsidwa ntchito kuthandizira kugwirizana kwa peptide ya carbodiimide-mediated popanga ester yogwira yapakatikati kudzera mwa condensation ya pamwamba carboxyl gulu ndi NHS.NHS-reactive ester intermediate imatha kugwidwa ndi nucleophilic ndi ma primary amines ndipo imapangitsa kuti pakhale mgwirizano wokhazikika wa amide pakati pa biomaterial pamwamba ndi N-terminus ya peptide.
N-Hydroxysuccinimide ndi hydroxylated succinimide yomwe imagwiritsidwa ntchito kwambiri poyambitsa ma carboxylic acid ku NHS-esters kulimbikitsa kulumikizana ndi ma nucleophiles.Njirayi imagwiritsidwa ntchito kwambiri poyambitsa mitundu ya asidi yaulere ya fluorophores polimbikitsa kulumikizana kwa ma fluorophore ndi zotsalira za amine zamapuloteni.Kugwiritsa ntchito NHS ester activation kwafotokozedwanso mu kaphatikizidwe ka N-acyl amino acid.
Amagwiritsidwa ntchito popanga amino acid protectant, semisynthetic kanamycin ndi pharmaceutical intermediates.N-hydroxybutyldiimide ndi zotumphukira zake ndizofunikira pakupangira ma peptides, maantibayotiki, ma amino acid ndi mapuloteni.N-hydroxybutyldiimide imagwiritsidwa ntchito pokonzekera yogwira ntchito. esters, ndi kuletsa kwa mphamvu ya optically yophatikizika ya peptide ili ndi ma NTCHITO osiyanasiyana muzamankhwala, komanso ndi mankhwala oyambira.
N-Hydroxysuccinimide imagwiritsidwa ntchito popititsa patsogolo njira ya carbodiimide.Amagwiritsidwanso ntchito kuyambitsa gulu la carboxyl ndikuchitapo kanthu ndi amine kupanga amide.Imakhudzidwa ndikukonzekera kwa N-hydroxymaleimide-styrene copolymer.
N-Hydroxysuccinimide inakonzedwa motere: 100g (1.0mol) succinic anhydride ndi 70g (1.0mol) ya hydroxylamine hydrochloride imatenthedwa palimodzi, machitidwewa amasungidwa pansi pa zovuta zoipa kuti achotse kuphulika kwaiye, ndipo amatenthedwa mofulumira kufika pamwamba pa 125 ℃. , kenako imakwera pang'onopang'ono mpaka 160 ℃ pambuyo pa 1H.Kutentha kunayimitsidwa ndipo kutentha kutsika kufika pa 125 ℃, madziwo amathiridwa mu diethyl ether ndikugwedezeka mwamphamvu.Mankhwalawa atachiritsidwa, wosanjikiza wa ether adachotsedwa, mankhwala ochiritsidwa adatenthedwa mpaka kuwira ndi 400ml ya butanol, osefedwa otentha, ndipo filtrate idakhazikika mwachangu mpaka 0 ℃.Pambuyo pa kusefedwa kwa 1H, makhiristo adatsukidwa motsatizana ndi butanol ndi diethyl ether, ndipo zomwe adapeza zidasinthidwanso kuchokera ku ethyl acetate kuti apeze 50g yazinthu zomalizidwa muzokolola za 44%.
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