Olmesartan Medoxomil CAS 144689-63-4 Purity>99.5% (HPLC) API Factory
Ruifu Chemical Supply Olmesartan Medoxomil Intermediate With High Quality:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Dzina la Chemical | Olmesartan Medoxomil |
Mawu ofanana ndi mawu | 4-(1-Hydroxy-1-methylethyl)-2-propyl-1--[[2'-(2H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H- imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester;Mtengo wa CS-866 |
Nambala ya CAS | 144689-63-4 |
Nambala ya CAT | Chithunzi cha RF-PI1730 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C29H30N6O6 |
Kulemera kwa Maselo | 558.60 |
Melting Point | 180 ℃ (Dec.) |
Kusungunuka kwamadzi | Zosasungunuka m'madzi;Zosungunuka pang'ono mu DMSO |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera mpaka Pafupifupi Woyera Cyrstalline |
Chizindikiritso | IR, HPLC, UV: Iyenera Kugwirizana ndi Reference Standard |
Kuyera / Kusanthula Njira | >99.5% (HPLC pa Anhydrous and Solvent-Free Basis) |
Kutaya pa Kuyanika | <0.50% |
Zotsalira pa Ignition | <0.10% |
Zogwirizana nazo | |
Olmesartan RRT 0.2 | <0.50% |
Olmesartan Medoxoil Related Compound A. RRT 0.7 | <0.20% |
Olefinic Impurity RRT 1.6 | <0.50% |
N-Alkyl Impurity RRT 3.4 | <0.10% |
Chidetso China Chilichonse | <0.10% |
Zonse Zonyansa | <0.50% |
Zitsulo Zolemera (monga Pb) | <10ppm |
pH ya Solution (2%, W/V) | 4.5 mpaka 6.5 |
Test Standard | Enterprise Standard;USP Standard |
Kugwiritsa ntchito | API |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
Olmesartan Medoxomil (CS-866) (CAS: 144689-63-4) ndi amphamvu komanso kusankha angiotensin II mtundu 1 (AT (1)) receptor antagonist ndi IC50 ya 66.2 μM., yogwiritsidwa ntchito pochiza kuthamanga kwa magazi.Amagwiritsidwa ntchito ngati antihypertensive.Olmesartan imagwira ntchito poletsa kumangirira kwa angiotensin II ku zolandilira za AT1 mu minofu yam'mitsempha.Poletsa kumangirira m'malo mopanga angiotensin II, Olmesartan imalepheretsa kuwongolera koyipa kwa katulutsidwe ka renin.Olmesartan Medoxomil ndi pro-mankhwala omwe amachotsedwa ku metabolite yogwira, olmesartan.Olmesartan Medoxomil idakhazikitsidwa ku US ngati Benicar, chithandizo choperekedwa pakamwa cha matenda oopsa.