Olopatadine Hydrochloride Intermediate CAS 27710-82-3 Purity>99.0% (HPLC)
Wotsogola Wotsogola wa Olopatadine Hydrochloride Intermediates
Olopatadine Hydrochloride CAS 140462-76-6
Isoxepac CAS 55453-87-7
[3-(Dimethylamino)propyl]triphenylphosphonium Bromide Hydrobromide CAS 27710-82-3
Please Contact: alvin@ruifuchem.com
Dzina la Chemical | [3-(Dimethylamino)propyl]triphenylphosphonium Bromide Hydrobromide |
Mawu ofanana ndi mawu | (3-Dimethylaminopropyl) triphenylphosphonium Bromide HBr |
Nambala ya CAS | 27710-82-3 |
Nambala ya CAT | Mtengo wa RF2698 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | Mtengo wa C23H28Br2NP |
Kulemera kwa Maselo | 509.27 |
Melting Point | 283.0 ~ 285.0 ℃ |
Kukhazikika | Hygroscopic |
Kusungunuka | Chloroform (Pang'ono), Methanol (Pang'ono) |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera mpaka Woyera wa Crystal |
Kuyera / Kusanthula Njira | >99.0% (HPLC) |
Njira Yoyesera / Kusanthula | >99.0% (Chiwerengero) |
Kutaya pa Kuyanika | <0.50% |
Chidetso Chimodzi | <0.50% |
Zonse Zonyansa | <1.00% |
1 H NMR Spectrum | Zogwirizana ndi Kapangidwe |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Pakati pa Olopatadine Hydrochloride (CAS: 140462-76-6) |
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[3-(Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide (CAS: 27710-82-3) ndi yapakatikati ya Olopatadine Hydrochloride (CAS: 140462-76-6).Olopatadine Hydrochloride ndi anti-allergenic mankhwala.Zili ndi zotsatira ziwiri zomwe zimalepheretsa kutulutsidwa kwa histamine komanso kusokoneza HI receptors, ndipo ilibe choletsa chapakati cha mitsempha ndi zotsatira za poizoni wa mtima zomwe zimakhala zofala ndi HI receptor antagonist antiallergic drugs.Olopatadine Hydrochloride sangalepheretse kutulutsidwa kwa histamine kuchokera ku maselo a mast, komanso kutsutsa ma receptor a H1 mosankha, ndipo alibe mphamvu pa α adrenergic receptors, dopamine receptors, ndi M1 ndi M2 receptors.Pakati pawo, zotsatira zapakati pa mitsempha yapakati ndizochepa, ndi mbadwo watsopano wa mankhwala oletsa antiallergic osankhidwa.Olopatadine ndi mdani wamphamvu, wosankha wa H1 histamine receptor (Ki = 16-41.1 nM), yokhala ndi ma affinities otsika kwambiri a H2 ndi H3 receptors (Ki = 43.4 ndi 172 μM, motsatira).Imalepheretsa kutembenuka kwa histamine-induced phosphoinositide m'maselo akutali (IC50 = 9.5-39.9 nM) ndipo imalepheretsa anaphylaxis yamtundu wa makoswe (ED50 = 49 μg / kg) ndi anaphylactic bronchoconstriction mu Guinea nkhumba (ID50 = 30 μg / kg).Olopatadine ndi othandiza pochiza matupi awo sagwirizana rhinitis ndi conjunctivitis.Imachepetsanso kuyabwa kwa odwala omwe ali ndi urticaria yoyendetsedwa bwino.Kwa anthu, antihistamine iyi siyambitsa kuwonongeka kwa chidziwitso kapena psychomotor pamankhwala achire.