Palbociclib CAS 571190-30-2 Purity>99.5% (HPLC) API Factory
Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
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Dzina la Chemical | Palbociclib |
Mawu ofanana ndi mawu | PD-0332991;Otava-BB 1115529;Ibrance |
Nambala ya CAS | 571190-30-2 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C24H29N7O2 |
Kulemera kwa Maselo | 447.54 |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera kapena Woyera |
1H NMR Spectrum | Zogwirizana ndi Kapangidwe |
Mtengo wa HPLC | Zogwirizana ndi Kapangidwe |
Zogwirizana nazo | |
Chidetso cha Munthu Payekha | <0.50% |
Zonse Zonyansa | <1.00% |
Kutaya pa Kuyanika | <0.50% |
Zotsalira pa Ignition | <0.10% |
Zitsulo Zolemera | <10ppm |
Kuyera / Kusanthula Njira | > 99.5% (HPLC) |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | API, Pochiza Khansa ya M'mawere |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
Palbociclib (CAS: 571190-30-2) ndi inhibitor yopezeka pakamwa ya cyclin-dependent kinase (CDK) yokhala ndi zochita za antiineoplastic.Palbociclib mosankha amaletsa cyclin-dependent kinase 4 (CDK4) ndi 6 (CDK6), potero amaletsa retinoblastoma (Rb) protein phosphorylation koyambirira kwa gawo la G1 zomwe zimatsogolera kumangidwa kwa cell.Izi zimachepetsa kugawanika kwa DNA ndikuchepetsa kuchuluka kwa maselo otupa.Palbociclib ndi woimira woyamba wa gulu latsopano la mankhwala la cyclin-dependent kinase inhibitors.Izi zimalepheretsa kukula kwa maselo (kukula ndi kugawanika kwa maselo).Amagwiritsidwa ntchito ngati antineoplastic agent mu khansa ya m'mawere yapamwamba kapena metastatic.