Palonosetron Hydrochloride CAS 135729-62-3 Purity >99.0% (HPLC) (T) API Factory

Kufotokozera Kwachidule:

Dzina la Mankhwala: Palonosetron Hydrochloride

CAS: 135729-62-3

Maonekedwe: Ufa Woyera Kapena Woyera Wamakristalo

Kuyera: > 99.0% (HPLC) (T)

Palonosetron Hydrochloride ndi wamphamvu kwambiri, wosankha komanso wogwira ntchito pakamwa 5-HT3 receptor antagonist yomwe imagwiritsidwa ntchito popewa ndi kuchiza chemotherapy-induced nseru ndi kusanza (CINV).Antiemetic.

Lumikizanani ndi Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

Inquiry: alvin@ruifuchem.com

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Zogulitsa Zamalonda Palonosetron Hydrochloride ndi Zapakati Zofananira:
(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R) -1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S) -3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API

Chemical Properties:

Dzina la Chemical	Palonosetron Hydrochloride
Mawu ofanana ndi mawu	Palonosetron HCl;(S,S)-Palonosetron Hydrochloride;RS-25259;RS25259 197;(S) -2-((S)-Quinuclidin-3-yl) -2,3,3a,4,5,6-Hexahydro-1H-Benzo[de]isoquinolin-1-one Hydrochloride;(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-Hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride ;Aloxi;Onicit
Nambala ya CAS	135729-62-3
Nambala ya CAT	RF-API03
Stock Status	Mu Stock, Kupanga Kukula Mpaka Matani
Molecular Formula	Mtengo wa C19H24N2O·HCl
Kulemera kwa Maselo	332.87
Mkhalidwe Woyenera Kupewa	Kutentha Kwambiri
Melting Point	307 ℃ (Dec.)
Kusungunuka mu Madzi	Zosungunuka Kwambiri M'madzi
Kusungunuka	Kwambiri Pang'ono Kusungunuka mu Ethanol
Kutentha Kotumiza	Ambient Kutentha
COA & MSDS	Likupezeka
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Ufa Woyera kapena Woyera wa Crystalline
Palonosetron Hydrochloride	>99.0% (HPLC) (T)
Kusinthasintha Kwachindunji [α]20/D	-98.0°～-104.0°
Chizindikiritso	Onjezani BiI7K4, Pangani Mtsinje Wachikasu Wa Orange
Chizindikiritso	TLC Yogwirizana ndi Reference Substance
Chizindikiritso	IR Yogwirizana ndi Standard IR
Chizindikiritso	Kuzindikiridwa ngati Chloride
Kusungunuka	Zosungunuka mwaulere m'madzi, zosungunuka pang'ono mu Methanol, sungunuka pang'ono mu Mowa, wosasungunuka mu acetone
Kumveka ndi Mtundu wa Solution	Max.Yellow No. 2 Standard Color Solution
Phindu la pH	4.5 ~ 6.5 (10mg/ml)
Zogwirizana
Zogwirizana ndi A (NO)	<0.10%
Related Compound B (Ene-NO)	<0.10%
Gulu lofananira C (S,R)	<0.10%
Gulu D (R,S)	<0.50%
Palonosetron Enantiomer	<0.10%
Gulu E (3-Ene)	<0.50%
Chidetso Chimodzi Chosazindikirika	<0.10%
Zosungunulira Zotsalira
Ethanol	<3000ppm
Tetrahydrofuran	<5000ppm
DMF	<880ppm
Normal Hexane	<290ppm
Mowa wa Methyl	<3000ppm
Isopropanol	<5000ppm
Methylbenzene	<890ppm
Madzi	<0.30%
Zotsalira pa Ignition	<0.20%
Kutaya pa Kuyanika	<1.00%
Zitsulo Zolemera	<10ppm
Test Standard	United States Pharmacopoeia (USP);European Pharmacopoeia (EP)
Kugwiritsa ntchito	Palonosetron Hydrochloride API;5-HT3 Wotsutsa;Mtengo wa CINV

Phukusi & Kusungira:

Phukusi: Botolo, Cardboard Drum, 25kg / Drum, kapena malinga ndi zomwe kasitomala akufuna.

Posungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.

Ubwino:

FAQ:

Ntchito:

Palonosetron Hydrochloride (CAS: 135729-62-3) ndi mankhwala oletsa nseru ndi kusanza, womwe ndi mtundu watsopano wosankha kwambiri, wogwirizana kwambiri ndi 5-HT3 receptor antagonist yomwe ingalepheretse kusanza kwa reflex center peripheral neurons presynaptic 5-HT.Chisangalalo cholandirira chimakhudza mwachindunji dongosolo lapakati lamanjenje mu 5-HT.Chisangalalo cholandira cholandilira chopangidwa ndi gawo la vagal afferent mitsempha pambuyo pa malo, kutsekereza mathero a mitsempha ya vagus m'matumbo, kuteteza ma sign ku 5-HT.Receptor trigger zone imatha kuchepetsa kuchuluka kwa nseru ndi kusanza.Central kuchipatala zochizira pachimake kwambiri emetogenic chemotherapy anachititsa kuchedwa nseru ndi kusanza.Chifukwa cha kuchiritsa kwake kwakukulu, zotsatira zake zochepa, theka la moyo wautali (pafupifupi 40 h), mlingo wochepa, ndi zina zotero, zakopa chidwi kwambiri.

Ndi 1,2,3,4-Tetrahydro-1-Naphthoic Acid monga chiyambi, kugawanika, amination, kuchepetsa, cyclization, mchere wa palonosetron hydrochloride granisetron.Kafukufuku wachipatala anasonyeza kuti palonosetron angagwiritsidwe ntchito bwinobwino ndi corticosteroids, analgesics, antiemetics, antispasmodics ndi anticholinergic mankhwala monga poyambira zinthu, kugawanika, amination, kuchepetsa, cyclization, mchere wa palonosetron hydrochloride granisetron.