Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1 Assay 97.5 ~ 102.0% Factory
Ruifu Chemical Supply With High Purity
Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1
N-Methyl Paroxetine CAS 110429-36-2
Dzina la Chemical | Paroxetine Hydrochloride Hemihydrate |
Mawu ofanana ndi mawu | (3S,4R)-(-)-3- [(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride Hemihydrate;Paxil;Seroxat;BRL29060 Hydrochloride Hemihydrate;BRL29060A Hemihydrate;Paroxetine-D4 HCl |
Nambala ya CAS | 110429-35-1 |
Nambala ya CAT | Chithunzi cha RF-PI1946 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C19H20FNO3·HCl·1/2H2O |
Kulemera kwa Maselo | 374.84 |
Melting Point | 140.0 ~ 143.0 ℃ |
Kusinthasintha Kwachindunji [α]20/D | -88.0° mpaka -92.0° (C=1, MeOH, Calcd.on anh.substance) |
Kusungunuka | Zosasungunuka m'madzi;Zosungunuka kwambiri mu Dimethylformamide, Methanol;Zosungunuka mu Ethanol |
Mtundu | Ruifu Chemical |
Zamkatimu | Zofotokozera | Zotsatira |
Maonekedwe | Ufa Woyera Kapena Woyera Wamakristalo | Gwirizanani |
Chizindikiro A | Mayamwidwe a infrared spectrum ayenera kukhala ogwirizana ndi mawonekedwe | Gwirizanani |
Chizindikiro B | Malo apamwamba kwambiri ndi nthawi yosungira yankho la mayesero ayenera kugwirizana ndi yankho lachidziwitso | Gwirizanani |
Chizindikiro C | Madzi (mwa KF) | Gwirizanani |
Chizindikiritso D | Kuchita kwa Kloridi | Gwirizanani |
Chidebe D | ≤0.20% | Kulibe |
Zoyipa G | ≤0.001% | |
Zogwirizana nazo | Chidetso A: ≤0.30% | 0.03% |
Zoyipa Zosadziwika: Pa chodetsa chilichonse, ≤0.10% | 0.06% | |
Zonse Zosafunika: ≤0.50% | 0.10% | |
Zitsulo Zolemera | ≤0.002% | <0.002% |
Madzi (mwa KF) | 2.20% ~ 2.70% | 2.46% |
Phulusa la Sulfated | ≤0.10% | <0.10% |
Kuyesa | 97.5% ~ 102.0% (Chinthu Chopanda Madzi) | 100.2% |
Zosungunulira Zotsalira | ||
Methanol | ≤0.30% | 0.001% |
Acetone | ≤0.50% | 0.001% |
Isopropanol | ≤0.50% | 0.04% |
Dichloromethane | ≤0.06% | Palibe |
Toluene | ≤0.089% | 0.003% |
Kutsiliza: Kugwirizana ndi EP7.0. |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
Paroxetine Hydrochloride Hemihydrate (CAS: 110429-35-1) ndi imodzi mwazamphamvu kwambiri komanso yosankha serotonin reuptake inhibitors (SSRI);antidepressant.Ndiwochokera ku phenylpiperidine, ndi yamphamvu kwambiri komanso yosankha ST (serotonin transporter/5-HT) uptake inhibitor.Zimagwira ntchito pomanga ST (serotonin transporter/SERT) yokhala ndi kuyanjana kwakukulu (Ki = 05 nM).Antidepressant ndi anxiolytic mu vivo.Paroxetine hydrochloride angagwiritsidwe ntchito pochiza kuvutika maganizo, amene ndi mankhwala atsopano antidepressant.Itha kugwiritsidwanso ntchito pochiza mantha, kusokonezeka kwanthawi zonse, kusokonezeka kwa chikhalidwe cha anthu, vuto la obsessive-compulsive disorder (OCD), kusowa tulo, premenstrual syndrome, kutulutsa umuna msanga ndi matenda ena, ndikuchiritsa bwino komanso zotsatirapo zochepa.Chitani mitundu yonse ya kupsinjika maganizo.Kuphatikizirapo kukhumudwa ndi nkhawa komanso kupsinjika kokhazikika.Zizindikiro zodziwika bwino za kupsinjika maganizo: kutopa, kusokonezeka kwa kugona, kusowa chidwi ndi kusangalala ndi ntchito za tsiku ndi tsiku, kusowa kwa njala.Pambuyo pakukhutitsidwa kwa machiritso, kumatha kupewa kuyambiranso kwa kukhumudwa.