Pirfenidone CAS 53179-13-8 Purity ≥99.0% IPF
Perekani Ndi Kuyera Kwambiri, Kupanga Zamalonda
Dzina la mankhwala: Pirfenidone
CAS: 53179-13-8
| Dzina la Chemical | Pirfenidone |
| Mawu ofanana ndi mawu | Perfenidone;5-Methyl-1-Phenylpyridine-2 (1H) -imodzi;PFD;S-7701;AMR-69 |
| Nambala ya CAS | 53179-13-8 |
| Nambala ya CAT | RF-API108 |
| Stock Status | Zilipo |
| Molecular Formula | C12H11NO |
| Kulemera kwa Maselo | 185.22 |
| Melting Point | 96.0 mpaka 97.0 ℃ |
| Kusungunuka | Zosungunuka mu DMSO |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Wakristalo Woyera mpaka Wachikasu |
| Chizindikiritso | IR |
| Chiyero | ≥99.0% |
| Kutaya pa Kuyanika | ≤0.50% |
| Phulusa la Sulfated | ≤0.20% |
| Chidetso Chimodzi | ≤0.50% |
| Zonse Zonyansa | ≤1.0% |
| Zitsulo Zolemera | ≤20ppm |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | API, Idiopathic Pulmonary Fibrosis (IPF) |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.
Pirfenidone (CAS: 53179-13-8) ili m'gulu la mankhwala otchedwa antifibrotic agents.Pirfenidone yawonetsa kuchitapo kanthu mumitundu yambiri yama fibrotic, kuphatikiza m'mapapo, impso ndi chiwindi.Zimakhudza chitetezo cha mthupi lanu ndipo zimachepetsa kuchuluka kwa fibrosis (zipsera) m'mapapu.Pirfenidone ndi amodzi mwamankhwala awiri omwe amavomerezedwa ku Canada kuchiza Idiopathic Pulmonary Fibrosis (IPF).Pirfenidone ndi inhibitor ya TGF-β kupanga ndi TGF-β yolimbikitsa kupanga collagen, imachepetsa kupanga TNF-α ndi IL-1β, komanso imakhala ndi anti-fibrotic ndi anti-inflammatory properties.Anavomerezedwa koyamba ku Japan kuti azichiza odwala omwe ali ndi idiopathic pulmonary fibrosis pambuyo pa mayesero a zachipatala, pansi pa dzina la malonda la Pirespa ndi Shionogi, mu 2008. United States mu October 2014.
