Posaconazole CAS 171228-49-2 API Factory Triazole Antifungal Agent High Quality
Factory Supply Posaconazole Related Intermediates, Commercial Production
Posaconazole CAS 171228-49-2
Posaconazole Wapakatikati POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2 - [(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+)-Tartrate CAS 87-91-2
Dzina la Chemical | Posaconazole |
Mawu ofanana ndi mawu | POS;SCH 56592;4-- [4-4-- [[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl] methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-imodzi |
Nambala ya CAS | 171228-49-2 |
Nambala ya CAT | RF-API77 |
Stock Status | Mu Stock, Kupanga Kufikira Mazana a Kilogram |
Molecular Formula | Chithunzi cha C37H42F2N8O4 |
Kulemera kwa Maselo | 700.78 |
Kuchulukana | 1.36g/cm3 |
Kusungunuka | Suluble mu DMSO, Insoluble m'madzi |
Mkhalidwe Wotumiza | Kutumizidwa Pansi pa Kutentha Kozungulira |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Wa Crystalline Woyera mpaka Woyera |
Chizindikiro A | IR: Mayamwidwe amtundu wa infrared a chinthucho akuyenera kugwirizana ndi zomwe zikuwonetsedwa. |
Chizindikiro B | HPLC Kusunga nthawi yofanana ndi zinthu zolozera |
Melting Point | 167.0 ~ 171.0 ℃ |
Kuzungulira Kwachindunji [a]20 | -24.0° ~ -28.0° (C=1, CHCL3) |
Madzi (KF) | ≤1.0% |
Zotsalira pa Ignition | ≤0.10% |
Zogwirizana nazo | |
Chithunzi cha HT909-24 | ≤0.20% |
Chidetso Chilichonse Chamunthu | ≤0.10% |
Zonse Zonyansa | ≤1.0% |
Zosungunulira Zotsalira | |
Methanol | ≤3000ppm |
Methyl tert-Butyl Ether | ≤5000ppm |
Isopropanol | ≤5000ppm |
Dimethyl Sulfoxide | ≤5000ppm |
Dichloromethane | ≤600ppm |
Kuyesa | 98.0% ~ 102.0% (Yowerengedwa pa zouma) |
Zitsulo Zolemera | ≤10ppm |
Isomer | Enantiomer ≤0.10% |
Chidetso Chilichonse Payekha ≤0.10% | |
Zonse Zosafunika ≤1.0% | |
Test Standard | Enterprise Standard;USP;BP;EP Standard |
Kugwiritsa ntchito | API, Triazole Antifungal Agent |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Posaconazole (CAS 171228-49-2), ndi m'badwo wachiwiri, wa triazole wokhala ndi antifungal, womwe unakhazikitsidwa ku UK, ndiye membala watsopano kwambiri wa gulu la azole la antifungal agents kuti afike pamsika.Amasonyezedwa pochiza ndi kuteteza matenda osiyanasiyana a mafangasi, kuphatikizapo aspergillosis, fusariosis, chromoblastomycosis, mycetoma, ndi coccidiomycosis kwa odwala omwe amakana, kapena osalolera, chithandizo chokhazikika ndi amphotericin B ndi/kapena itraconazole.Ku US, amavomerezedwa kuti atetezere matenda a Aspergillus ndi Candida kwa odwala azaka 13 omwe ali pachiwopsezo chachikulu chotenga matendawa chifukwa chokhala osatetezedwa kwambiri.Kuphatikiza apo, amavomerezedwa kuti azichiza oropharyngeal candidiasis.Posaconazole ali ndi kukodzedwa sipekitiramu ntchito kuposa ena a azole antifungals.Kuphatikiza pa ntchito zamphamvu zotsutsana ndi milandu yotsutsana ndi aspergillosis ndi fluconazole-resistant Candida, imasonyeza ntchito yolimbana ndi Zygomycetes.Posaconazole ndi mankhwala a triazole antifungal omwe amagulitsidwa ku United States ndi Schering-Plough pansi pa dzina la malonda Noxafil.