Potaziyamu Bis(trimethylsilyl)amide CAS 40949-94-8 (0.5M Solution mu Toluene)
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Dzina la Chemical | Potaziyamu Bis (trimethylsilyl) amide |
Mawu ofanana ndi mawu | Hexamethyldisilazane Potaziyamu Mchere;Potaziyamu Hexamethyldisilazane;Zithunzi za KHMDS |
Nambala ya CAS | 40949-94-8 |
Nambala ya CAT | RF-PI2227 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C6H18KNSi2 |
Kulemera kwa Maselo | 199.49 |
Boiling Point | 111 ℃ |
Kuchulukana | 0.877 g/mL pa 25 ℃ |
Kalasi Yowopsa | 3 (8);Madzi Oyaka, Owononga |
Packing Group | II |
Kusungunuka | Zosakaniza Ndi Terahydrofuran, Ether, Benzene ndi Toluene |
Kusungunuka kwamadzi | Amachita Ndi Madzi |
Hydrolytic Sensitivity | 8: Imachita Mofulumira Ndi Chinyezi, Madzi, Zosungunulira za pProtic |
Kukhazikika | Imamva Chinyezi, Imamva Kutentha, Imamva Kutentha.Sungani Pansi pa Nayitrogeni.Akhoza Kupanga Mvula.Kutentha kozungulira. |
Chitetezo | Zowopsa-Malipiro Owonjezera a Katundu Wowopsa Angagwire Ntchito |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Yellow to Brown Liquid |
Zonyansa Zina | ≤3.00% |
Zomwe zili mu Active Base | 0.45 ~ 0.55 M |
Test Standard | Enterprise Standard |
Phukusi:Botolo, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Zimamva chinyezi ndi mpweya.Sungani pamalo ozizira.Sungani chidebe chotsekedwa mwamphamvu pamalo owuma komanso mpweya wabwino.Zotengera zomwe zatsegulidwa ziyenera kutsekedwa bwino ndikusungidwa kuti zisatayike.Gwirani ndi kusunga pansi pa gasi wa inert.Zosagwirizana ndi ma oxidizing amphamvu.
Ndemanga Zowopsa:Zamadzimadzi zoyaka kwambiri komanso nthunzi.Zimayambitsa kutentha kwambiri kwa khungu komanso kuwonongeka kwa maso.Zimayambitsa kuwonongeka kwa maso.Amaganiziridwa kuti akuwononga chonde kapena mwana wosabadwa.Zikhoza kuwononga ziwalo chifukwa cha nthawi yayitali kapena mobwerezabwereza.Zitha kuyambitsa kugona kapena chizungulire.
Potaziyamu Bis(trimethylsilyl)amide (0.5M Solution mu Toluene) (kawirikawiri amafupikitsidwa ngati KHMDS) (CAS: 40949-94-8) ndi maziko amphamvu, osakhala a nucleophilic okhala ndi pKa pafupifupi 26 (yerekezerani ndi lithiamu diisopropylamide, pa 36 ).Imapezeka pamalonda ngati yolimba komanso ngati yankho mu zosungunulira zosiyanasiyana (monga THF, 2Me-THF, toluene, ndi MTBE).Ma reagents ofanana ndi akuti lithium bis(trimethylsilyl)amide (LiHMDS) ndi sodium bis(trimethylsilyl)amide (NaHMDS).Non-nucleophilic megasteric strong base.Pharmaceutical intermediates, ntchito kupanga kupanga cephalosporins.Zithunzi za KHMDSndi mankhwala omwe amagwiritsidwa ntchito pokonzekera chromatography yamadzimadzi yokonzekera kwambiri.Amagwiritsidwa ntchito popanga zovuta zokhazikika ndi potaziyamu, zomwe zimasiyanitsidwa ndi gawo.KHMDS imagwiritsidwanso ntchito pofufuza zamankhwala achilengedwe komanso ngati chothandizira cha asymmetric synthesis.KHMDS ndi maziko amphamvu omwe amagwiritsidwa ntchito mumagulu a alkylation carbonyl.KHMDS imagwiritsidwa ntchito pokonzekera 5-Azacytidine, mankhwala a antiineoplastic.Amagwiritsidwanso ntchito pokonzekera ma β3-AR agonists omwe amagwiritsidwa ntchito popanga anti-stress formulations.Amagwiritsidwanso ntchito ngati reagent pokonza ma complexes a lanthanide omwe amagwiritsidwa ntchito posankha ma cyclization.