Pregabalin CAS 148553-50-8 Purity>99.0% (HPLC) Antiepileptic API

Pregabalin ndi mankhwala a antiepileptic a m'badwo wachiwiri (AED) omwe amadziwika ndi dzina la Lyrica (Pfizer, Tadworth) ku UK ndi USA, okhala ndi γ-amino butyric acid kapangidwe kake ka maselo, omwe amakhala ndi anticonvulsant, bwino zopangidwa ndi kampani Pfizer zochizira zotumphukira neuropathic ululu, kapena adjuvant chithandizo cha khunyu pang`ono.Pregabalin ndi mankhwala a Anticonvulsant ndi antiepileptic omwe amagwiritsidwa ntchito pochiza khunyu, ululu wa neuropathic, fibromyalgia, ndi matenda osokonezeka maganizo.Kugwiritsiridwa ntchito kwake kwa khunyu kumakhala ngati chithandizo chowonjezera cha khunyu pang'ono kapena popanda kuwonjezereka kwachiwiri kwa akuluakulu.Mu Disembala 2008, US Food and Drug Administration (FDA) idavomereza pregabalin (dzina lamalonda "Lyrica") kuti azichiza matenda a diabetic peripheral neuropathic pain (DPN) ndi postherpetic neuralgia (PHN) omwe ndi onse omwe amawawa kwambiri a neuropathic.Pregabalin ili ndi chisonyezo chovomerezeka ndipo imagwiritsidwa ntchito kwambiri pochiza matenda anthawi zonse.Mayesero angapo osasinthika, akhungu awiri, oyendetsedwa ndi placebo adapeza kuti pregabalin ndi chithandizo chothandiza kwa odwala omwe ali ndi vuto lanthawi zonse komanso nkhawa zamagulu.Mlingo wa titration Khunyu-adjunctive therapy: 25 mg bd kwa masiku 7, kuwonjezeka ndi 50 mg masiku 7 aliwonse;yokonza mwachizolowezi 300 mg tsiku, ogaŵikana 2 kapena 3 Mlingo (max. 600 mg tsiku, ogaŵikana 2 kapena 3 Mlingo).Generalized nkhawa matenda: 150 mg tsiku, ogaŵikana 2 kapena 3 Mlingo, kwa masiku 7, kuti ziwonjezeke ndi 150 mg aliyense 7 masiku (max. 600 mg tsiku, ogaŵikana 2 kapena 3 Mlingo).Ngati muyimitsa pregabalin, tikulimbikitsidwa kuti tidutse kwa sabata imodzi kuti mupewe kusiya mwadzidzidzi.Chenjezo Odwala omwe ali ndi mikhalidwe yomwe ingayambitse encephalopathy.Odwala kwambiri congestive mtima kulephera.