Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Purity ≥98.5% (GC) Vonoprazan Fumarat Intermediate Factory
Supply Vonoprazan Fumarate ndi Related Intermediate
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
Dzina la Chemical | Pyridine-3-Sulfonyl Chloride |
Mawu ofanana ndi mawu | 3-Pyridinesulfonyl Chloride;3-Pyridylsulfonyl Chloride;m-Pyridinesulfonyl Chloride;Piperidine-3-Sulfonylchloride |
Nambala ya CAS | 16133-25-8 |
Nambala ya CAT | RF-PI540 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | Chithunzi cha C5H4ClNO2S |
Kulemera kwa Maselo | 177.61 |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Madzi Opanda Mtundu kapena Otuwa Wachikasu |
Kuyera / Kusanthula Njira | ≥98.5% (GC) |
Boiling Point | 110.0 ~ 112.0 ℃/2mm Hg |
Chidetso Chimodzi | ≤0.50% |
Zonse Zonyansa | ≤1.5% |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Pakati pa Vonoprazan Fumarate (CAS: 1260141-27-2) |
Phukusi: Botolo, 25kg / Barrel, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.
Pyridine-3-Sulfonyl Chloride (CAS: 16133-25-8) ndi yapakatikati ya Vonoprazan Fumarate (CAS: 1260141-27-2).Vonoprazan Fumarate, yomwe idapezeka ndikupangidwa ndi Takeda ndi Otsuka, idavomerezedwa ndi PMDA yaku Japan mu Disembala 2014, ndipo imawonetsedwa pochiza zilonda zam'mimba, zilonda zam'mimba ndi reflux esophagitis.Vonoprazan fumarate ali ndi buku limagwirira zochita otchedwa potaziyamu-mpikisano asidi blockers, amene mpikisano ziletsa kumanga ayoni potaziyamu H+, K+ -ATPase (amatchedwanso pulotoni mpope) mu sitepe yomaliza ya chapamimba asidi katulutsidwe mu chapamimba parietal maselo.Vonoprazan saletsa Na+, K+ -ATPase ntchito ngakhale pa ndende nthawi 500 kuposa IC50 makhalidwe awo motsutsana chapamimba H+, K+ -ATPase ntchito.Komanso, mankhwalawa sakhudzidwa ndi chapamimba secretory state, mosiyana ndi PPIs.