(R) -(+) -2-Methyl-CBS-oxazaborolidine;(R)-Me-CBS Catalyst CAS 112022-83-0 Optical Purity ≥98.0%

Kupereka kwa opanga;Ubwino Wapamwamba ndi Mtengo Wopikisana

CBS Catalysts
(S)-(-)-2-Methyl-CBS-oxazaborolidine;(S)-Me-CBS Chothandizira (ca. 1mol / L mu Toluene);CAS: 112022-81-8
(R) -(+) -2-Methyl-CBS-oxazaborolidine;(R) -Me-CBS Chothandizira (ca. 1mol / L mu Toluene);CAS: 112022-83-0

CBS Catalyst
Chothandizira cha CBS kapena Corey-Bakshi-Shibata chothandizira ndi chothandizira cha asymmetric chochokera ku proline.Amapeza ntchito zambiri pamachitidwe achilengedwe monga kuchepetsa CBS, Diels-Alder reactions ndi (3+2) cycloadditions.Proline, mankhwala a chiral omwe amapezeka mwachilengedwe, amapezeka mosavuta komanso otsika mtengo.Imasamutsa stereocenter yake kupita ku chothandizira chomwe chimatha kuyendetsa organic reaction kumodzi mwa ma enantiomers awiri.Kusankha uku kumachitika chifukwa cha kupsinjika kwapakati pakusintha komwe kumapangidwira enantiomer imodzi koma osati ina.

CBS Catalysts for Asymmetric Reduction and Asymmetric Synthesis
CBS (Corey-Bakshi-Shibata) oxazaborolidine chothandizira chagwiritsidwa ntchito pochepetsa asymmetric a prochiral ketones.Ntchito zina zikuphatikizapo enantioselective synthesis ya α-hydroxy acids, α-amino acid, C2-symmetrical ferrocenyl diols, ndi propargyl alcohols.

(R) - (+) -2-Methyl-CBS-oxazaborolidine (ca. 1mol / L mu Toluene) CAS: 112022-83-0 angagwiritsidwe ntchito ngati chothandizira mu asymmetric borane kuchepetsa perfluoroalkyl ketones.Ntchito zina zikuphatikizapo enantioselective synthesis ya α-hydroxy acids, α-amino acid, C2 symmetrical ferrocenyl diols, ndi propargyl alcohols.Amagwiritsidwanso ntchito pochepetsa desymmetrizing kupita ku (S) -4-hydroxycyclohexenone.Ndizothandiza popanga ma stereospecific motifs monga α-hydroxy acid, α-amino acid, symmetrical ferrocenyl diols ndi propargyl alcohols.

(R) - (+) -2-Methyl-CBS-oxazaborolidine (ca. 1mol / L mu Toluene) CAS: 112022-83-0 ndi organoboron catalyst yomwe imagwiritsidwa ntchito popanga organic synthesis.Chothandizira ichi, chopangidwa ndi Itsuno ndi Elias James Corey, chimapangidwa ndi kutentha (R) - (+) -2- (diphenylhydroxymethyl) pyrrolidine pamodzi ndi trimethylboroxine kapena methylboronic acid.Ndi chida chabwino kwambiri chopangira ma alcohols mu kuchuluka kwa enantiomeric.Nthawi zambiri, 2-10 mol% ya chothandizira ichi imagwiritsidwa ntchito limodzi ndi borane-tetrahydrofuran (THF), borane-dimethylsulfide, borane-N, N-diethylaniline, kapena diborane monga gwero la borane.Kuchepetsa kwa enantioselective pogwiritsira ntchito chiral oxazaborolidine catalysts kwagwiritsidwa ntchito popanga mankhwala osokoneza bongo monga ezetimibe ndi aprepitant.