Ramelteon (TAK-375) CAS 196597-26-9 Chiyero>99.5% (HPLC)

Kufotokozera Kwachidule:

Dzina la Chemical: Ramelteon

Mawu ofanana: TAK-375;Rozerem®

CAS: 196597-26-9

Kuyera:> 99.5% (HPLC)

Maonekedwe: White Crystalline Ufa

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E-Mail: alvin@ruifuchem.com

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Kufotokozera:

Wopanga Wotsogola ndi Wopereka, Wapakati wa Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-imodzi CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com

Chemical Properties:

Dzina la Chemical	Ramelteon
Mawu ofanana ndi mawu	(S)-N-[2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethyl]propionamide;TAK-375;TAK375;TAK 375;Rozerem
Nambala ya CAS	196597-26-9
Nambala ya CAT	Mtengo wa RF2885
Stock Status	Mu Stock, Kupanga Kukula Mpaka Matani
Molecular Formula	C16H21NO2
Kulemera kwa Maselo	259.35
Melting Point	113.0 mpaka 116.0 ℃
Boiling Point	455.3±24.0℃
Kuchulukana	1.119±0.06 g/cm3
Kusinthasintha Kwachindunji [α]20/D	-55.0° mpaka -60.0° (C=1, CHCL3)
Kusungunuka mu Madzi	Zosasungunuka m'madzi (11 mg/l 25 ℃)
Kusungunuka	Zosungunuka mu Ethanol, Methanol, DMSO
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	White Crystalline Powder
Kuyera / Kusanthula Njira	> 99.5% (HPLC)
Melting Point	113.0 ~ 116.0 ℃
Kutaya pa Kuyanika	<0.50%
Zotsalira pa Ignition	<0.10%
Isomer Purity	<0.10%
Zitsulo Zolemera	<10ppm
Acidity kapena alkalinity	Gwirizanani
Ethanol	<5000ppm
Chidetso Chimodzi	<0.20%
Zonse Zonyansa	<0.50%
Infrared Spectrum	Zimagwirizana ndi Kapangidwe
Test Standard	Enterprise Standard
Kugwiritsa ntchito	API, Yovomerezeka pa Chithandizo cha Insomnia

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi

Ubwino:

Mphamvu Zokwanira: Malo okwanira ndi akatswiri

Utumiki Waukatswiri: Ntchito imodzi yosiya kugula

Phukusi la OEM: Phukusi lamwambo ndi zolemba zilipo

Kutumiza Mwachangu: Ngati mkati mwa katundu, kuperekedwa kwamasiku atatu kumatsimikizika

Zinthu Zokhazikika: Khalani ndi katundu wokwanira

Thandizo laukadaulo: Yankho laukadaulo likupezeka

Custom Synthesis Service: Kuchokera pa magalamu mpaka ma kilos

Ubwino Wapamwamba: Anakhazikitsa dongosolo lathunthu lotsimikizira zaubwino

FAQ:

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Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.

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UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.

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Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.

Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.

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Ntchito:

Ramelteon (CAS: 196597-26-9) idavomerezedwa koyamba ndi US Food and Drug Administration (FDA) pa Julayi 22, 2005, kenako idavomerezedwa ndi Pharmaceuticals and Medical Devices Agency (PMDA) pa Apr 16, 2010. Idapangidwa ndipo kugulitsidwa ngati Rozerem® ndi Takeda,angagwiritsidwe ntchito pochiza kusowa tulo movutikira kugona, ndipo ali ndi zotsatira zotsimikizika pa kusowa tulo kosatha komanso kusowa tulo kwakanthawi.Izi zitha kusankha mtundu wa 1 ndi mtundu wa 2 zolandilira melatonin (MT1, MT2), kukulitsa kugona pang'onopang'ono (SWS) ndi kugona tulo kofulumira (REW), potero kumachepetsa kugona.Ramelteamide ndiye mankhwala oyamba osagwiritsa ntchito tulo omwe sali pansi pa ulamuliro wapadera.Izi ndi melatonin receptor agonist.Ili ndi kuyanjana kwakukulu ndi melatonin MT1 ndi MT2 receptors, ndipo imakhala ndi mphamvu yeniyeni komanso yokwanira ya agonistic pa MT1 ndi MT2 receptors, koma sichimalumikizana ndi MT3 receptor.Kuphatikiza apo, sichimangirira ku ma neurotransmitter receptors monga GABA receptor complexes, ndipo sichimasokoneza ntchito ya ma enzymes ambiri mkati mwamtundu wina.Chifukwa chake, imatha kupewa kusokoneza komwe kumakhudzana ndi mankhwala a GABA (omwe angayambitse ngozi zagalimoto, kugwa ndi kusweka).Etc.) ndi kumwerekera ndi mankhwala osokoneza bongo komanso kudalira.Rozerem® imapezeka ngati piritsi lokutidwa ndi filimu kuti ligwiritsidwe ntchito pakamwa, lomwe lili ndi 8 mg ya Ramelteon yaulere.Mlingo woyenera wa munthu wamkulu ndi 8 mg wotengedwa mkati mwa mphindi 30 mutagona.