Rapamycin Sirolimus RAPA CAS 53123-88-9 Assay ≥98.5% API Factory High Purity
Wopanga ndi Kuyera Kwambiri ndi Ubwino Wokhazikika
Dzina la Mankhwala: Rapamycin;Sirolimus;RAPA
CAS: 53123-88-9
Macrolide Immunosuppressive Agent
API High Quality, Commercial Production
Dzina la Chemical | Rapamycin |
Mawu ofanana ndi mawu | Sirolimus;RAPA;AY-22989 |
Nambala ya CAS | 53123-88-9 |
Nambala ya CAT | RF-API59 |
Stock Status | Mu Stock, Kupanga Kufikira Mazana a Kilogram |
Molecular Formula | C51H79NO13 |
Kulemera kwa Maselo | 914.19 |
Melting Point | 183.0 ~ 185.0 ℃ |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera kapena Woyera wa Crystalline |
Chizindikiro A | The IR sipekitiramu ya potaziyamu bromide yokonzekera zitsanzo imawonetsa maxima pamlingo wofanana ndi wa kukonzekera kofananako kwa mulingo wapanyumba. |
Chizindikiro B | The UV sipekitiramu wa 95% Mowa kukonzekera chitsanzo zimasonyeza maxima pa 267nm, 277nm, 288nm monga kukonzekera kofananako m'nyumba zofotokozera muyezo. |
Chizindikiro C | Nthawi yosungira nsonga za trans-ndi cis-stereoisomers mu chromatogram ya kukonzekera assay imafanana ndi yomwe ili mu chromatogram yokonzekera muyeso, monga momwe zapezedwa mu assay. |
Kuzungulira kwa Optical | -147.0°~ -157.0° |
Kutaya pa Kuyanika | ≤0.50% |
Zotsalira pa Ignition | ≤0.20% |
Zitsulo Zolemera | ≤20ppm |
Chidetso cha Munthu Payekha | ≤1.5% |
Zonse Zonyansa | ≤2.0% (kupatula Cis-Stereoisomer ya Sirolimus) |
Cis-Stereoisomer wa Sirolimus | ≤5.0% |
Zosungunulira Zotsalira | |
Ethanol | ≤5000ppm |
Ethyl Acetate | ≤5000ppm |
Cyclohexane | ≤5000ppm |
Acetone | ≤5000ppm |
Diethyl Ether | ≤5000ppm |
Kuyesa | ≥98.5% (Yowerengedwa trans- ndi cis-stereoisomer ya sirolimus pamaziko a dired) |
Test Standard | Chinese Pharmacopoeia (CP);Enterprise Standard |
Kugwiritsa ntchito | Active Pharmaceutical Ingredient (API) |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Rapamycin (Sirolimus; AY 22989) ndi autophagy activator, mtundu watsopano wa macrolide immunosuppressive agent wokhala ndi zotsatira zabwino zochiritsa, kawopsedwe kochepa, komanso wopanda nephrotoxicity.Itha kugwiritsidwa ntchito posungira chitetezo cha ziwalo zoberekera (makamaka poika impso) kuti muchepetse kukana kwa immunological pambuyo pa maopaleshoni oyika ziwalo.