Remdesivir GS-5734 CAS 1809249-37-3 COVID-19 API High Quality

Kufotokozera Kwachidule:

Dzina la Chemical: Remdesivir (GS-5734)

CAS: 1809249-37-3

Maonekedwe: Ufa Woyera mpaka Woyera

Chiwerengero: 98.0% ~ 102.0%

Remdesivir pochiza COVID-19

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Opanga Zogulitsa Zamalonda Remdesivir ndi Othandizira Ofananira Ndi Ubwino Wapamwamba
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Wapakatikati CAS 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1

Chemical Properties:

Dzina la Chemical	Remdesivir
Mawu ofanana ndi mawu	GS-5734;2-ethylbutyl ((S)-((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano -3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Nambala ya CAS	1809249-37-3
Nambala ya CAT	RF-API96
Stock Status	Mu Stock, Kupanga Kufikira Mazana a Kilogram
Molecular Formula	Chithunzi cha C27H35N6O8P
Kulemera kwa Maselo	602.58
Kuchulukana	1.47±0.1 g/cm3
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Ufa Wolimba mpaka Woyera
Chizindikiro A	IR: Mayamwidwe amtundu wa infrared a chinthucho akuyenera kugwirizana ndi zomwe zikuwonetsedwa.
Chizindikiro B	HPLC Kusunga nthawi yofanana ndi zinthu zolozera
Kuzungulira Kwapadera	-19.0° ~ -22.0°
Kusungunuka	Zosungunuka mu Methanol, Zosungunuka Mochepa mu Ethanol, Zosungunuka Pang'ono mu Acetonitrile, Zosasungunuka M'madzi
Zogwirizana nazo
Chidetso Chilichonse Chamunthu	≤0.10%
Zonse Zonyansa	≤1.0%
RD-3.1	≤0.10%
RD-C	≤0.10%
RD-D	≤0.10%
RD-E	≤0.10%
RP-Isomer	≤0.10%
Nitrophenol	≤0.10%
Zosungunulira Zotsalira
Methanol Dichloride	≤6000ppm
Acetone	≤5000ppm
Mowa wa Isopropyl	≤5000ppm
Acetonitrile	≤410ppm
Dichloromethane	≤600ppm
Methyl tert Butyl Ether	≤5000ppm
Ethyl Acetate	≤5000ppm
Tetrahydrofuran	≤720ppm
n-Heptane	≤5000ppm
Kuyesa	98.0% ~ 102.0% (Yowerengedwa pa zouma)
Total Aerobic Counts
Mabakiteriya Aerobic	≤100cfu/g
Yisiti ndi Mold	≤10cfu/g
E. Kolo	Zoipa
Bakiteriya Endotoxin	≤1.0EU
Zitsulo Zolemera	≤20ppm
Test Standard	Enterprise Standard
Kugwiritsa ntchito	API, COVID-19

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.

Ubwino:

FAQ:

Ntchito:

Remdesivir (CAS 1809249-37-3), yogulitsidwa pansi pa dzina la Veklury, ndi mankhwala oletsa ma virus omwe amapangidwa ndi kampani ya biopharmaceutical Gilead Sciences.Amaperekedwa kudzera mu jekeseni mumtsempha.Panthawi ya mliri wa COVID-19, remdesivir idavomerezedwa kapena kuloledwa kugwiritsidwa ntchito mwadzidzidzi pochiza COVID-19 m'maiko pafupifupi 50.Malangizo osinthidwa kuchokera ku World Health Organisation mu Novembala 2020 akuphatikiza malingaliro oletsa kugwiritsa ntchito Remdesivir pochiza COVID-19.Remdesivir adapangidwa kuti azichiza matenda a hepatitis C, ndipo adafufuzidwa za matenda a Ebola virus komanso matenda a Marburg virus asadaphunziridwe ngati chithandizo chapambuyo pa COVID-19.Zotsatira zodziwika kwambiri mwa odzipereka athanzi ndikukweza kuchuluka kwa ma enzymes a chiwindi (chizindikiro cha vuto la chiwindi).Zotsatira zoyipa kwambiri mwa anthu omwe ali ndi COVID-19 ndi nseru.Zotsatira zake zingaphatikizepo kutupa kwa chiwindi ndi kulowetsedwa kokhudzana ndi kulowetsedwa ndi nseru, kuchepa kwa magazi, ndi kutuluka thukuta.Remdesivir ndi mankhwala omwe amapangidwa kuti alole kuperekedwa kwa intracellular ya GS-441524 monophosphate ndi zotsatira za biotransformation mu GS-441524 triphosphate, ribonucleotide analogue inhibitor ya viral RNA polymerase.