Roflumilast CAS 162401-32-3 Assay 99.0~101.0% API

Kufotokozera Kwachidule:

Dzina la mankhwala: Roflumilast

CAS: 162401-32-3

Kuyesa: 99.0 ~ 101.0% (Yowerengedwa pa Maziko Ouma)

Maonekedwe: Ufa Woyera Kapena Woyera Wamakristalo

API PDE-4 Inhibitor COPD

Lumikizanani ndi Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Ruifu Chemical Supply Roflumilast Intermediates:
Roflumilast CAS 162401-32-3
4-Amino-3,5-Dichloropyridine CAS 22889-78-7

Chemical Properties:

Dzina la Chemical	Roflumilast
Mawu ofanana ndi mawu	3-(Cyclopropylmethoxy)-N-(3,5-Dichloropyridin-4-yl)-4-(Ddifluoromethoxy)benzamide
Nambala ya CAS	162401-32-3
Nambala ya CAT	RF-PI2075
Stock Status	Mu Stock, Kupanga Kukula Mpaka Matani
Molecular Formula	C17H14Cl2F2N2O3
Kulemera kwa Maselo	403.21
Kuchulukana	1.471±0.060 g/cm3
Kumverera	Kutentha Kwambiri
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Ufa Woyera Kapena Woyera Wamakristalo
Kusungunuka	Zosungunuka zaulere mu acetone, zosungunuka pang'ono mu acetronitrile, zosasungunuka pang'ono mu anhydrous ethanol, pafupifupi osasungunuka m'madzi.
Melting Point	157.0 ~ 162.0 ℃
Kutaya pa Kuyanika	<0.50%
Zotsalira pa Ignition	≤0.10%
Zitsulo Zolemera	≤10ppm
Chloride	≤0.01%
Chizindikiritso A. UV	Kutalika kwa mayamwidwe apamwamba kuyenera kukhala 213 ~ 251nm
Chizindikiritso B. IR	Kuchuluka kwa mayamwidwe a IR kwa zitsanzo kumafanana ndi komwe kumatchulidwa
Chizindikiro C.	Zimawonetsa zomwe Fluoride amachita
Zogwirizana nazo
Chidetso Chimodzi	≤0.10%
Zonse Zonyansa	<0.50%
Zosungunulira Zotsalira
Tert-Butanol	<0.10%
Tetrahydrofuran	<0.072%
Toluene	<0.089%
N, N-Dimethylformamide	<0.088%
Kuyesa	99.0 ~ 101.0% (Yowerengedwa pa Maziko Ouma)
Test Standard	Enterprise Standard
Kugwiritsa ntchito	API;COPD

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi

Ubwino:

FAQ:

Ntchito:

Roflumilast (CAS: 162401-32-3) ndi oral phosphodiesterase-4 (PDE-4) inhibitor yosankhidwa ndi benzamide compound.Idapangidwa ndi kampani yaku Germany ya Altana mu 1993 ndipo ndiyo yokha yapakamwa ya PDE-4 inhibitor yomwe imagwiritsidwa ntchito pochiza matenda am'mimba ovomerezeka kugulitsidwa.Roflumilast ndi mankhwala oyamba amtundu wake kulimbana ndi matenda oopsa a obstructive pulmonary disease (COPD), komanso ndi mankhwala oletsa kutupa pakamwa omwe amapangidwira odwala COPD.Makhalidwe ake apadera angathandize kuwongolera COPD: akagwiritsidwa ntchito limodzi ndi bronchodilators pochiza odwala kwambiri COPD, Roflumilast akhoza kukhala ndi mwayi wochepetsera zizindikiro ndi kuchepa kwa chiwerengero, motero kupanga mankhwala oyamba omwe amalimbana ndi odwala omwe akuwonongeka mobwerezabwereza phenotype-spAecific COPD. ndi kutsekeka kwakukulu kwa mpweya wokhudzana ndi chifuwa chosatha ndi phlegm yambiri.Kupatula kukhala chithandizo cha COPD yoopsa, Roflumilast angagwiritsidwenso ntchito kupewa ndi kuchiza matenda a m'mapapo a ziweto, chifuwa chachikulu cha mucosa bronchitis, chifuwa cha mphumu, bronchitis ndi air sacculitis motsatizana ndi katulutsidwe ka kupuma kovutirapo.