Rosuvastatin Calcium CAS 147098-20-2 Assay 98.5%~102.0% API Factory High Purity
Perekani ndi Kuyera Kwambiri ndi Ubwino Wokhazikika
Rosuvastatin kashiamu
CAS: 147098-20-2
Kupanga Zamalonda
Dzina la Chemical | Rosuvastatin kashiamu |
Mawu ofanana ndi mawu | ZD 4522 Calcium;(E) -6--[4-(4-Fluorophenyl)-6-Isopropyl-2-(Methyl-Methylsulfonyl-amino)pyrimidin-5-yl]-2,4-Dihydroxy-hex-5-Enoate;(6E)-7-{4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(methylsulfonyl) amino]pyrimidin-5-yl}-3,5-Dihydroxyhept-6-Enoic Acid |
Nambala ya CAS | 147098-20-2 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | Mtengo wa C44H54CaF2N6O12S2 |
Kulemera kwa Maselo | 1001.14 |
Melting Point | 122 ℃ |
Mkhalidwe Wotumiza | Kutumizidwa Pansi pa Kutentha Kozungulira |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera mpaka Woyera |
Kuzungulira Kwapadera | + 17.0 ° ~ +21.0 ° |
Chizindikiritso | A. Chimakwaniritsa Chofunikira B. UV: λmax = 243nm C. IR: Zofanana ndi Zofotokozera D. X-Ray: Zofanana ndi Reference Substance |
Chloride | ≤0.10% |
Sulphate | ≤0.10% |
Enantiomer | ≤0.15% |
Calcium Yopezeka | 3.5% ~ 4.5% |
Zogwirizana nazo | |
Diastereomer | ≤0.15% |
5-Oxo-Rosucastatin | ≤0.15% |
Kuwonongeka kwa Zithunzi 1 | ≤0.15% |
Kuwonongeka kwa Zithunzi 2 | ≤0.15% |
Rosuvastatin Lactone | ≤0.15% |
Rosuvastatin Methyl Ester | ≤0.15% |
Rosuvastatin Isoamyl Ester | ≤0.15% |
Chidetso Chilichonse Chosadziwika | ≤0.10% |
Zonse Zonyansa | ≤0.75% |
Chinyezi (KF) | ≤3.0% |
Chitsulo Cholemera | ≤20ppm |
Isoamyl Bromide | ≤37.5ppm |
Zosungunulira Zotsalira | |
Ethyl Ether | ≤300ppm |
Acetonitrile | ≤410ppm |
Isoamyl Mowa | ≤5000ppm |
DMF | ≤880ppm |
Kuyesa | 98.5% ~ 102.0% (yowerengedwa pa maziko a anhydrous) |
Test Standard | Enterprise Standard;BP/USP/EP Standard |
Kugwiritsa ntchito | API |
Phukusi: Botolo, mbiya, makatoni ng'oma, 25kg / mbiya, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi
Rosuvastatin Calcium (CAS: 147098-20-2) ndi mankhwala oletsa hyperlipidemia omwe ali a inhibitor ya HMG-CoA reductase yopangidwa bwino ndi kampani ya British AstraZeneca.Ndiwoyenera kuchiza matenda osiyanasiyana a lipid, kuphatikiza hypercholesterolemia, zovuta zamtundu wa lipid komanso hypertriglyceridemia yosavuta.Rosuvastatin Calcium (CAS: 147098-20-2) imatchulidwa kuti ndi mankhwala amphamvu kwambiri komanso ophatikizana kwambiri a statins omwe alowa mumsika wotsitsa lipid-kutsitsa ndikusintha.Poyerekeza ndi atorvastatin yomwe imadziwika kuti ndiyothandiza kwambiri padziko lonse lapansi, imakhala ndi zotsatira zabwino zotsitsa cholesterol ya LDL ndikuwonjezera kuchuluka kwa lipoprotein yapamwamba kwambiri.Komanso, ali kulolerana bwino, m'munsi zotsatira ndi wapadera pharmacokinetic makhalidwe ndi theka moyo pafupifupi 20h.