(S) -1-Boc-3-Hydroxypiperidine CAS 143900-44-1 Ibrutinib Intermediate Purity >99.0% (GC)

Kufotokozera Kwachidule:

Dzina Lamankhwala: (S) -1-Boc-3-Hydroxypiperidine

CAS: 143900-44-1

Chiral Purity: >99.0% (GC)

Chemical Purity:> 99.0% (GC)

Maonekedwe: Ufa Woyera kapena Makhiristo

Pakati pa Ibrutinib (CAS: 936563-96-1)

Ubwino Wapamwamba, Kupanga Zamalonda

E-Mail: alvin@ruifuchem.com

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Zogwirizana ndi Ibrutinib:
(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1
4-Phenoxyphenylboronic Acid CAS 51067-38-0
Ibrutinib Wapakatikati N-2 CAS 330786-24-8
Ibrutinib Wapakatikati N-3 CAS 330792-70-6
Ibrutinib CAS 936563-96-1

Chemical Properties:

Dzina la Chemical	(S) -1-Boc-3-Hydroxypiperidine
Mawu ofanana ndi mawu	(S) -1-(tert-Butoxycarbonyl) -3-Hydroxypiperidine;(S) -1-Boc-3-Piperidinol
Nambala ya CAS	143900-44-1
Nambala ya CAT	Mtengo wa RF-CC299
Stock Status	Mu Stock, Mphamvu Yopanga Matani 20 / Mwezi
Molecular Formula	C10H19NO3
Kulemera kwa Maselo	201.27
Melting Point	52.0 ~ 56.0 ℃
Kusungunuka	Zosungunuka mu Methanol
Kusinthasintha Kwachindunji [a]20/D	+9.0°~+11.0° (C=1 mu Chloroform)
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Ufa Woyera kapena Makristasi
Chiral Purity	>99.5% (GC)
Chemical Purity	>99.5% (GC)
Madzi (KF)	≤0.50%
Methanol (GC)	≤50ppm
Ethanol (GC)	≤50ppm
DCM (GC)	≤500ppm
3-Hydroxypiperidine	≤0.10%
3-Hydroxypyridine	≤0.20%
1-Boc-3-Piperidone	≤0.10%
1-Boc-4-Hydroxypiperidine	≤0.10%
Mtengo wa 1.96	≤0.20%
Chidetso Chilichonse Chosadziwika	≤0.10%
Test Standard	Enterprise Standard
Kugwiritsa ntchito	Pharmaceutical Intermediates;Chiral Compounds

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.

Ubwino:

FAQ:

Ntchito:

(S) -1-Boc-3-Hydroxypiperidine (CAS: 143900-44-1) ndizofunikira kwambiri zapakati pa kaphatikizidwe ka Ibrutinib (CAS: 936563-96-1).Ibrutinib ndi mtundu wa Bruton tyrosine kinase (BTK) inhibitor, ukhoza kugwiritsidwa ntchito pochiza matenda a lymphocytic leukemia (CLL) ndi mantle cell lymphoma (MCL).MCL ndi CLL ndi a B-cell non-Hodgkin's lymphoma, omwe ndi ovuta kuchiza komanso osavuta kubwereza.Ma immunotherapy wamba alibe cholinga, nthawi zambiri amapezeka 3 kapena 4 zoyipa.Ibrutinib ndi B lymphocytes akhoza kulunjika ndi BTK yomwe ili yofunikira pakupanga, kusiyanitsa, ndi kufalitsa chidziwitso, kuletsa ntchito ya BTK mosasinthika, ndikuletsa kuchulukana kwa maselo otupa ndi kupulumuka bwino.Ibrutinib imatha kuyamwa mwachangu pambuyo pa makonzedwe amkamwa, pakadutsa 1 ~ 2h kufika pamlingo waukulu wamagazi, zotsatira zoyipa zimakhala za m'modzi kapena awiri, chifukwa chake, Ibrutinib idzakhala chisankho chatsopano chamankhwala a CLL ndi MCL.