Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Purity >99.0% (HPLC) API Factory High Quality

Kufotokozera Kwachidule:

Dzina la Chemical: Sitagliptin Phosphate Monohydrate

CAS: 654671-77-9

Chiyero:> 99.0% (HPLC pa zouma)

Maonekedwe: Ufa Woyera mpaka Woyera wa Crystalline

Zochizira matenda amtundu wa II shuga mellitus

API High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Perekani Sitagliptin Phosphate Monohydrate Zogwirizana:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Wapakatikati CAS 486460-21-3

Chemical Properties:

Dzina la Chemical	Sitagliptin Phosphate Monohydrate
Mawu ofanana ndi mawu	(R) -3-amino-1-(3-(trifluoromethyl) -5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4- (2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate
Nambala ya CAS	654671-77-9
Stock Status	Mu Stock, Kupanga Kukula Mpaka Matani
Molecular Formula	Chithunzi cha C16H20F6N5O6P
Kulemera kwa Maselo	523.3240802
Melting Point	202.0 ~ 204.0 ℃
Kusungunuka kwamadzi	Zosungunuka mu Madzi
Kuzungulira Kwapadera	-18.0°~-23.0° (C=1, Madzi)
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Ufa Wa Crystalline Woyera mpaka Woyera
Kuzindikiridwa ndi HPLC	Nthawi yosungira yachitsanzo ikugwirizana ndi muyezo
IR-Infrared Spectrum	IR Absorption Spectrum yachitsanzoyo iyenera kugwirizana ndi mawonekedwe amtundu wamba
Phosphate	Zimagwirizana
Kuyera / Kusanthula Njira	> 99.0% (HPLC pa zouma)
M'madzi (KF)	3.3% ~ 4.4%
Zotsalira pa Ignition	≤0.20%
Sulphate	≤0.02%
Chloride	≤0.05%
Chiral Impurity	<0.50%
Zogwirizana nazo
Chidetso Chimodzi	<0.50%
Zonse Zonyansa	<1.0%
Ethyl Acetate	<0.50%
Zitsulo Zolemera	<20ppm
Test Standard	Enterprise Standard
Kugwiritsa ntchito	Pharmaceutical Intermediates

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.

Ubwino:

FAQ:

Ntchito:

Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9), mankhwala atsopano ochizira matenda amtundu wa 2.Mu Ogasiti 2009, mankhwalawa adavomerezedwa ndi European Union ngati mankhwala oyamba ochizira matenda amtundu wa 2.Sitagliptin Phosphate ndiye choletsa choyamba chovomerezedwa ndi FDA chovomerezeka ndi dipeptidyl peptidase-IV kuti chigwiritsidwe ntchito pochiza matenda amtundu wa 2 mpaka pano, pansi pa dzina lamalonda la Januvia.Dipeptidylpeptidase Ⅳ (DPP-Ⅳ) imatsitsa mwachangu komanso moyenera GLP-1, GLP-1, chomwe ndi chothandizira kwambiri kupanga insulini komanso katulutsidwe Chifukwa chake, kuletsa kwa DPP-IV kumatha kupititsa patsogolo gawo la endogenous GLP-1, motero kumawonjezera magazi. insulini, potero kuchepetsa ndi kusunga milingo ya shuga m'magazi mwa odwala matenda ashuga.Pakalipano, mankhwala atsimikizira kuti DPP-IV inhibitor ndi mtundu watsopano wa mankhwala oletsa matenda a shuga, ndipo zotsatira zachipatala zimasonyeza kuti mankhwalawa ali ndi zotsatira zabwino za hypoglycemic.Chifukwa GLP-1 imatenga gawo lodalira shuga polimbikitsa kupanga ndi kutulutsa kwa insulini, zovuta zomwe zimachitika nthawi zambiri monga hypoglycemia ndi kuwonda komwe kumachitika chifukwa chogwiritsa ntchito mankhwala a antidiabetic sikuchitika.