Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Purity >99.0% (HPLC) API Factory High Quality
Perekani Sitagliptin Phosphate Monohydrate Zogwirizana:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Wapakatikati CAS 486460-21-3
Dzina la Chemical | Sitagliptin Phosphate Monohydrate |
Mawu ofanana ndi mawu | (R) -3-amino-1-(3-(trifluoromethyl) -5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4- (2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate |
Nambala ya CAS | 654671-77-9 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | Chithunzi cha C16H20F6N5O6P |
Kulemera kwa Maselo | 523.3240802 |
Melting Point | 202.0 ~ 204.0 ℃ |
Kusungunuka kwamadzi | Zosungunuka mu Madzi |
Kuzungulira Kwapadera | -18.0°~-23.0° (C=1, Madzi) |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Wa Crystalline Woyera mpaka Woyera |
Kuzindikiridwa ndi HPLC | Nthawi yosungira yachitsanzo ikugwirizana ndi muyezo |
IR-Infrared Spectrum | IR Absorption Spectrum yachitsanzoyo iyenera kugwirizana ndi mawonekedwe amtundu wamba |
Phosphate | Zimagwirizana |
Kuyera / Kusanthula Njira | > 99.0% (HPLC pa zouma) |
M'madzi (KF) | 3.3% ~ 4.4% |
Zotsalira pa Ignition | ≤0.20% |
Sulphate | ≤0.02% |
Chloride | ≤0.05% |
Chiral Impurity | <0.50% |
Zogwirizana nazo | |
Chidetso Chimodzi | <0.50% |
Zonse Zonyansa | <1.0% |
Ethyl Acetate | <0.50% |
Zitsulo Zolemera | <20ppm |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Pharmaceutical Intermediates |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.
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Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9), mankhwala atsopano ochizira matenda amtundu wa 2.Mu Ogasiti 2009, mankhwalawa adavomerezedwa ndi European Union ngati mankhwala oyamba ochizira matenda amtundu wa 2.Sitagliptin Phosphate ndiye choletsa choyamba chovomerezedwa ndi FDA chovomerezeka ndi dipeptidyl peptidase-IV kuti chigwiritsidwe ntchito pochiza matenda amtundu wa 2 mpaka pano, pansi pa dzina lamalonda la Januvia.Dipeptidylpeptidase Ⅳ (DPP-Ⅳ) imatsitsa mwachangu komanso moyenera GLP-1, GLP-1, chomwe ndi chothandizira kwambiri kupanga insulini komanso katulutsidwe Chifukwa chake, kuletsa kwa DPP-IV kumatha kupititsa patsogolo gawo la endogenous GLP-1, motero kumawonjezera magazi. insulini, potero kuchepetsa ndi kusunga milingo ya shuga m'magazi mwa odwala matenda ashuga.Pakalipano, mankhwala atsimikizira kuti DPP-IV inhibitor ndi mtundu watsopano wa mankhwala oletsa matenda a shuga, ndipo zotsatira zachipatala zimasonyeza kuti mankhwalawa ali ndi zotsatira zabwino za hypoglycemic.Chifukwa GLP-1 imatenga gawo lodalira shuga polimbikitsa kupanga ndi kutulutsa kwa insulini, zovuta zomwe zimachitika nthawi zambiri monga hypoglycemia ndi kuwonda komwe kumachitika chifukwa chogwiritsa ntchito mankhwala a antidiabetic sikuchitika.
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Sitagliptin Phosphate Monohydrate CAS 654671-77...
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Sitagliptin CAS 486460-32-6 Chiyero>99.0% (HPLC...
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2,4,5-Trifluorophenylacetic Acid CAS 209995-38-...
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Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Buty...
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Sitagliptin Triazole Hydrochloride CAS 762240-9...
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Sitagliptin Phosphate Monohydrate Yapakatikati ...