Sorafenib CAS 284461-73-0 Purity ≥99.0% (HPLC) API Factory High Quality
Zogulitsa Zamalonda Sorafenib Tosylate ndi Zapakati Zofananira:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methylpicolinamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
| Dzina | Sorafenib |
| Mawu ofanana ndi mawu | Sorafenib Free Base |
| Nambala ya CAS | 284461-73-0 |
| Nambala ya CAT | RF-API04 |
| Stock Status | Mu Stock, Kupanga Kufikira Mazana a Kilogram |
| Molecular Formula | C21H16ClF3N4O3 |
| Kulemera kwa Maselo | 464.82 |
| Kuchulukana | 1.454±0.06 g/cm3 |
| Kusungunuka | Zosungunuka mu DMSO |
| Zoyenera Kutumiza | Ambient Kutentha |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Woyera mpaka Woyera |
| Kuyera / Kusanthula Njira | ≥99.0% (HPLC) |
| Chizindikiritso | H-NMR, MS |
| Kutaya pa Kuyanika | ≤1.0% |
| Zotsalira pa Ignition | ≤0.10% |
| Chidetso Chimodzi | ≤0.20% (HPLC) |
| Zonse Zonyansa | ≤1.0% (HPLC) |
| Zitsulo Zolemera | ≤20ppm |
| Kumveka kwa Yankho | Gwirizanani ndi Standard |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | RCC & HCC |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Sorafenib Tosylate (CAS: 475207-59-1) ndi mtundu watsopano wa mankhwala oletsa kutupa omwe ali ndi zolinga zambiri, adapangidwa ndi German Bayer Pharmaceuticals, ndipo adawonetsa ntchito yowonjezereka ya antitumor pamayesero anyama asanakwane.Sorafenib imapezeka m'mapiritsi a 200-mg pakamwa ndipo imagwiritsidwa ntchito pochiza RCC ndi HCC.Sorafenib Tosylate (CAS: 475207-59-1) imatha kukhudza nthawi yomweyo maselo a chotupa ndi mitsempha yamagazi.Imakhala ndi mphamvu yoletsa kutupa: imatha kuletsa njira zolumikizira ma cell zomwe zimalumikizidwa ndi RAF/MEK/ERK kuti ziletse mwachindunji kukula kwa cell chotupa, komanso kuletsa VEGF ndi mapulateleti opangidwa ndi kukula kwazinthu (PDGF) zolandilira kuteteza mapangidwe amagazi atsopano. ziwiya, motero mosalunjika kuletsa chotupa maselo kukula.Sorafenib ndi inhibitor ya Raf-1 ndi B-RAF komanso ma tyrosine kinases angapo.
