Telmisartan CAS 144701-48-4 Purity>99.5% (HPLC) API Factory
Ruifu Chemical Supply Telmisartan Imaphatikizana Ndi Kuyera Kwambiri
Telmisartan CAS 144701-48-4
Methyl 2-(p-Tolyl)benzoate CAS 114772-34-8
2-(p-Tolyl) benzoic Acid CAS 7148-03-0
Telmisartan Benzimidazole Acid CAS 152628-03-0
Telmisartan Methyl Ester CAS 528560-93-2
Methyl 2--[4-(Bromomethyl)phenyl]benzoate CAS 114772-38-2
Methyl 4-(Butyrylamino)-3-Methyl-5-Nitrobenzoate CAS 152628-01-8
2-n-Propyl-4-Methyl-6-(1-Methylbenzimidazole-2-yl)benzimidazole CAS 152628-02-9
Dzina la Chemical | Telmisartan |
Mawu ofanana ndi mawu | 4'- [[4-Methyl-6-(1-Methyl-1H-Benzimidazol-2-yl)-2-Propyl-1H-Benzimidazol-1-yl]methyl]biphenyl-2-Carboxylic Acid;4'-[(1,4'-Dimethyl-2'-propyl [2,6'-bi-1H-Benzimidazol]-1'-yl)methyl]-[1,1'-Biphenyl] -2-Carboxylic Acid |
Nambala ya CAS | 144701-48-4 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | Chithunzi cha C33H30N4O2 |
Kulemera kwa Maselo | 514.63 |
Melting Point | 261.0 ~ 263.0 ℃ |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera kapena Woyera wa Crystalline |
Kununkhira | Khalidwe |
Kusungunuka | Zosungunuka pang'ono mu Methylene Chloride, Zosungunuka pang'ono mu Methanol, Parctically Insoluble m'madzi, zimasungunuka mu 1M Solution Hydroxide |
Chizindikiro cha IR | Iyenera Kugwirizana ndi RS Infrared Absorption |
Chizindikiro cha HPLC | Nthawi Yosungitsa Pansonga Yaikulu Iyenera Kugwirizana ndi RS |
Kuyera / Kusanthula Njira | > 99.5% (HPLC) |
Kutaya pa Kuyanika | <1.00% |
Zotsalira pa Ignition | <0.10% |
Zogwirizana nazo | |
Telmisartan Related Compound A | <0.10% |
Telmisartan Amide | <0.10% |
Telmisartan Yogwirizana ndi Compound B | <0.10% |
Telmisartan Diacide | <0.10% |
Telmisartan Tert-Butyl Ester | <0.20% |
Telmisartan Unknown Unknown Impurity | <0.20% |
Chidetso Chosadziwika | <0.10% |
Zonse Zonyansa | <1.00% |
Zosungunulira Zotsalira | |
Methanol | <0.30% |
Ethanol | <0.50% |
Methylene Dichloride | <0.06% |
n-Hexane | <0.029% |
Acetic Acid Ethyl Ester | <0.50% |
Toluene | <0.089% |
Acetic Acid | <0.50% |
Zitsulo Zolemera | <10ppm |
Arsenic (As) | <1.00ppm |
Kutsogolera (Pb) | <1.00ppm |
Cadmium (Cd) | <1.00ppm |
Tinthu Kukula | D90 Osapitirira 15μm |
Kuchulukana Kwambiri (g/cc) | 0.11-0.20 |
Kuchulukirachulukira (g/cc) | 0.22-0.30 |
Mankhwala Otsalira | Zoipa |
Total Plate Count | <1000cfu/g |
Yisiti & Mold | <100cfu/g |
E. Coli | Zoipa |
Salmonella | Zoipa |
Test Standard | Enterprise Standard;USP 41 Standard |
Kugwiritsa ntchito | API |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
Telmisartan (CAS: 144701-48-4) ndi yochokera ku benzimidazole komanso si peptide angiotensin II receptor antagonist yokhala ndi antihypertensive katundu.Telmisartan mosankha imatsutsana ndi angiotensin II yomangiriza ku AT1 subtype receptor, yomwe ili mumitsempha yosalala ya mitsempha ndi adrenal gland.Kusagwirizanaku kumabweretsa vasodilation ndikulepheretsa kupanga kwa aldosterone ya angiotensin II, zomwe zimapangitsa kuchepa kwa sodium ndi madzi komanso kuwonjezeka kwa potaziyamu kumabweretsa kutsika kwa magazi.Telmisartan ndi mtundu watsopano wamankhwala othamanga kwa magazi, amagwiritsidwa ntchito payekha kapena kuphatikiza ndi magulu ena a antihypertensive pochiza matenda oopsa.Telmisartan idapangidwa koyambirira ndi kampani yaku Germany yopanga mankhwala Boehringer Ingelheim;idalandira chilolezo cha Germany EP502,314 mu 1991, idavomerezedwa koyamba kulowa mumsika waku America mu Novembala 1998, kenako idalowa m'misika yaku Germany, Philippines, Australia, Belgium, Britain, ndi misika ina.