Temozolomide (TMZ) CAS 85622-93-1 Assay 99.0%~101.0% API Factory High Purity
Perekani Temozolomide ndi Zophatikiza Zogwirizana:
Temozolomide CAS: 85622-93-1
4(5)-Amino-5(4)-Imidazolecarboxamide CAS: 360-97-4
5(4)-Amino-4(5)-Imidazolecarboxamide Hydrochloride CAS: 72-40-2
| Dzina la Chemical | Temozolomide |
| Mawu ofanana ndi mawu | 3,4-Dihydro-3-Methyl-4-Oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-Carboxamide |
| Nambala ya CAS | 85622-93-1 |
| Nambala ya CAT | RF-API29 |
| Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
| Molecular Formula | Chithunzi cha C6H6N6O2 |
| Kulemera kwa Maselo | 194.15 |
| Melting Point | 212 ℃ Dec. |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Woyera mpaka Wowala Wapinki |
| Chizindikiritso | Ndi IR, HPLC |
| Zosungunulira Zotsalira | Dimethyl Sulphoxide ≤0.50% |
| Zogwirizana nazo | |
| Chidebe cha AIC | ≤0.10% |
| Chidetso Chimodzi | ≤0.10% |
| Pumulani Zoyipa Zosadziwika | ≤0.30% |
| Zonse Zonyansa | ≤0.30% |
| Zitsulo Zolemera | ≤10ppm |
| Kutaya pa Kuyanika | ≤0.50% |
| Zotsalira pa Ignition | ≤0.10% |
| Kuyesa | 99.0% ~ 101.0% (HPLC pa zouma) |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | Active Pharmaceutical Ingredient (API) |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Shanghai Ruifu Chemical Co., Ltd. ndiye wopanga komanso wogulitsa Temozolomide (CAS: 85622-93-1) wokhala ndipamwamba kwambiri.Temozolomide (TMZ) ndi oral alkylating agent yomwe imagwiritsidwa ntchito pochiza Glioblastoma Multiforme (GBM) ndi Astrocytomas, Metastatic Melanoma.
Temozolomide ndiyo yoyamba yotengedwa pamlomo ngati imidazole ndi tetrazine-class anticancer mankhwala omwe ali m'badwo wachiwiri wa alkylating agent ndi antitumor ntchito popanda chiwindi kuyambitsa kagayidwe kachakudya pambuyo pakamwa.Amadziwika ndi kulowa mosavuta kudzera chotchinga magazi-ubongo, kulolerana bwino ndi kukhala superimposed ndi mankhwala ena kawopsedwe, ndi kukhala synergistic zotsatira ndi radiotherapy amene ali oyenera kuchiza zilonda glioma kuyambiranso pambuyo mankhwala ochiritsira monga glioblastoma multiforme zotupa kapena osachiritsika astrocytoma.Ndilo mankhwala oyamba ochizira metastatic melanoma.
Temozolomide idapangidwa koyamba ndi Cancer Research UK Group, kenako idasamutsidwa ku Schering-Plough Company (United States) kuti ipangidwe.Ili ndi kapangidwe kake katsopano ndipo ndi yamitundu ina ya imidazole.Mu 1999, idavomerezedwa kuti ilowe mumsika ku EU ndi ku US momwe chizindikiro chololedwa ku United States chimakhala chothandizira pamzere wachiwiri wa glioblastoma multiforme ndi degenerative star gliomas ndi zizindikiritso zovomerezeka za EU ndikuchiza matenda omwe akutukuka kapena kubwezeretsanso glioblastoma multiforme. zomwe zakhala zikuthandizidwa kale ndi mankhwala ochiritsira.Kuchita bwino kwa temozolomide pochiza glioblastoma multiforme kwadziwika kwambiri ku Europe.
