Tenofovir Alafenamide Hemifumarate TAF CAS 1392275-56-7 API Factory Anti-HIV High Quality

Kufotokozera Kwachidule:

Dzina: Tenofovir Alafenamide Hemifumarate (TAF)

CAS: 1392275-56-7

Makristalo Oyera mpaka Pafupifupi Oyera kapena Ufa Wa Crystalline

Chiwerengero: 98.0% ~ 102.0%

Mankhwala a Tenofovir, omwe amagwiritsidwa ntchito pophatikiza mankhwala ochizira HIV-1 Infection

Ubwino Wapamwamba, Kupanga Zamalonda

Inquiry: alvin@ruifuchem.com

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Zamalonda Zogwirizana ndi Tenofovir:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl Isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl)phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
Diethyl (Hydroxymethyl)phosphonate CAS 3084-40-0
Adenine CAS 73-24-5

Chemical Properties:

Dzina la Chemical	Tenofovir Alafenamide Hemifumarate
Mawu ofanana ndi mawu	TAF;GS-7340 Hemifumarate
Nambala ya CAS	1392275-56-7
Nambala ya CAT	RF-API91
Stock Status	Mu Stock, Kupanga Kufikira Mazana a Kilogram
Molecular Formula	Chithunzi cha C25H33N6O9P
Kulemera kwa Maselo	592.55
Kutentha Kosungirako	Kusindikizidwa mu Dry, Kutentha kwa Chipinda
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Makristalo Oyera mpaka Pafupifupi Oyera kapena Ufa Wa Crystalline
Kusungunuka	Zosungunuka mu Dimethylformamide, ndi Methanol;Zosungunuka pang'ono m'madzi ndi THF;Kusungunuka pang'ono mu Acetonitrile ndi Insoluble mu Dichloromethane ndi Toluene
Chizindikiro A	Mayamwidwe a IR ayenera kugwirizana ndi zomwe zikunenedwazo
Chizindikiro B	Nthawi yosungira pachimake chachikulu cha yankho lachitsanzo mu chromatogram yotsimikizira zomwe zili ikugwirizana ndi yankho lazofotokozera.
Chizindikiro C	Nthawi yosungira ya Fumaric Acid pachimake chachikulu mu chromatogram yotsimikizira zomwe zili mkati ikugwirizana ndi chiwongola dzanja chazofotokozera.
Mkati mwa Madzi (wolemba KF)	≤1.0%
Kumveka kwa Yankho	Kwenikweni palibe tinthu tating'onoting'ono mu 2% (w / v) ya Kufotokozera kwa Methanol Solution
Zosungunulira Zotsalira
Acetonitrile	≤410ppm
Ethanol	≤5000ppm
Dichloromethane	≤600ppm
Toluene	≤890ppm
Zotsalira pa Ignition	≤0.10%
Zitsulo Zolemera	≤20ppm
Zogwirizana nazo
PMPA	≤1.0%
Anhydride PMPA	≤0.75%
Single Phenyl PMPA	≤1.0%
Chidetso Chilichonse Chosadziwika	≤0.15%
Zonse Zonyansa	≤2.0%
Isomer	≤1.0%
Zomwe zili mu Fumaric Acid	9.0% ~ 13.0% (popanda madzi)
Malire a Microbial
Total Aerobic Microbial Count	≤1000CFU/g
Total Yisiti ndi Nkhungu Zimawerengera	≤100CFU/g
Escherichia Coli	Kulibe
Kuyesa	98.0% ~ 102.0% (pa maziko a anhydrous ndi zosungunulira)
Test Standard	Enterprise Standard

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.

Ubwino:

FAQ:

Ntchito:

Tenofovir Alafenamide Hemifumarate (TAF, GS-7340 hemifumarate), CAS 1392275-56-7, ndi nucleotide reverse transcriptase inhibitor (NRTIs) and novel prodrug of Tenofovir (TFV).Poletsa reverse transcriptase, TAF imateteza HIV kuti isachuluke ndipo imatha kuchepetsa kuchuluka kwa HIV mthupi.Tenofovir alafenamide ndi mankhwala, kutanthauza kuti ndi mankhwala osagwira ntchito.Mu thupi, tenofovir alafenamide imasinthidwa kukhala Tenofovir diphosphate (TFV-DP).Tenofovir Alafenamide Fumarate idavomerezedwa mu Novembala 2015 pochiza HIV-1.