Tolvaptan CAS 150683-30-0 API Purity >99.0% (HPLC)
Manufacturer Supply Tolvaptan ndi Intermediates Zogwirizana:
Tolvaptan CAS 150683-30-0
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Dzina | Tolvaptan |
Dzina la Chemical | N--[4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide |
Nambala ya CAS | 150683-30-0 |
Nambala ya CAT | RF-API101 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C26H25ClN2O3 |
Kulemera kwa Maselo | 448.94 |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Wa Crystalline Woyera mpaka Woyera |
Njira Zozindikiritsira | IR, HPLC |
Kusungunuka | Zosungunuka mu Benzyl Mowa ndi Methanol Koma Zosasungunuka mu Madzi ndi Hexane |
Kuyera / Kusanthula Njira | >99.0% (HPLC) |
Melting Point | 219.0 ~ 222.0 ℃ |
Kutaya pa Kuyanika | <0.50% |
Zotsalira pa Ignition | <0.10% |
Chidetso Chimodzi | <0.50% |
Zonse Zonyansa | <1.00% |
Zitsulo Zolemera | ≤20ppm |
Zosungunulira Zotsalira | Kumanani ndi Mafotokozedwe |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | API;Pharmaceutical Intermediates |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
Tolvaptan (CAS: 150683-30-0), yomwe imadziwikanso kuti OPC-41061, ndi wosankha, wopikisana wa arginine vasopressin receptor 2 antagonist omwe amagwiritsidwa ntchito pochiza hyponatremia (kuchepa kwa sodium m'magazi) okhudzana ndi kusokonezeka kwa mtima, cirrhosis, ndi matenda a mahomoni osayenera a antidiuretic (SIADH).Otsuka Pharmaceutical chilolezo tolvaptan pansi pa dzina malonda Samsca pambuyo FDA kuvomereza mankhwala mu May 2009. Tolvaptan wasonyezanso mphamvu polimbana polycystic impso matenda.M'mayesero a 2004, tolvaptan yogwiritsidwa ntchito ndi okodzetsa yachikhalidwe idadziwika kuti imachulukitsa kutulutsa kwamadzi ochulukirapo ndikuwongolera kuchuluka kwa sodium m'magazi mwa odwala omwe ali ndi vuto la mtima popanda kubweretsa zotsatira zoyipa monga hypotension (kutsika kwa magazi) kapena hypokalemia (kuchepa kwa potaziyamu m'magazi).Mankhwala komanso anasonyeza palibe mavuto impso ntchito.