Valsartan CAS 137862-53-4 Assay 98.0~102.0% API
Manufacturer Supply Valsartan ndi Intermediates Zogwirizana:
Valsartan CAS: 137862-53-4
L-Valine Methyl Ester Hydrochloride (H-Val-OMe·HCl) CAS: 6306-52-1
Dzina la Chemical | Valsartan |
Mawu ofanana ndi mawu | N-Valeryl-N-[2'-(1H-tetrazol-5-yl) biphenyl-4-ylmethyl]-L-valine |
Nambala ya CAS | 137862-53-4 |
Nambala ya CAT | RF-API32 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C24H29N5O3 |
Kulemera kwa Maselo | 435.52 |
Melting Point | 116.0 ~ 117.0 ℃ |
Kukhazikika | Hygroscopic |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera kapena Woyera;Zopanda fungo, Hygroscopic |
Chizindikiritso | Sipekitiramu ya IR yachitsanzo ikufanana ndi sipekitiramu yokhazikika |
Chizindikiritso | Nthawi yosungira pachimake chachikulu mu chromatogram ya kukonzekera kuyesa imagwirizana ndi kukonzekera kokhazikika, monga momwe zapezedwa mu Assay. |
Kusungunuka | Zosungunuka mu Methanol ndi Ethanol, Zosungunuka Mochepa mu Ethylacetate, Zosungunuka Pang'ono mu Dichloromethane, Zosasungunuka mu Madzi |
Chinyezi (KF) | ≤1.00% |
Absorbance (420mm) | ≤0.02% (λ=420nm, C=0.05g/ml, L=1cm) |
Zotsalira pa Ignition | ≤0.10% |
Zitsulo Zolemera | ≤10ppm |
D-Valsartan | ≤1.00% (HPLC) |
Zogwirizana (HPLC) | |
Butyryl-Valsartan | ≤0.20% |
Benzyl-Valsartan | ≤0.10% |
Chisalungamo Chosadziwika Chokha | ≤0.10% |
Zonse Zonyansa | ≤0.30% (Kupatula D-Valsartan) |
Zosungunulira Zotsalira (GC) | |
Methanol | ≤3000ppm |
Ethyl Acetate | ≤5000ppm |
N, N-Dimethylformamide | ≤880ppm |
Toluene | ≤890ppm |
Kuyera / Kusanthula Njira | > 99.0% (HPLC yowerengedwa pa maziko a anhydrous, opanda zosungunulira) |
Test Standard | United States Pharmacopoeia (USP) |
Kugwiritsa ntchito | Active Pharmaceutical Ingredient (API) |
Valsartan (CAS: 137862-53-4) Njira Yopangira Mayendedwe
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga ndi kugulitsa Valsartan (CAS: 137862-53-4) yokhala ndipamwamba kwambiri.Valsartan ndi nonpeptide angiotensin II AT1 receptor antagonist, Antihypertensive, ali ndi kuthekera kwa kuthamanga kwa magazi komanso kulephera kwa mtima kafukufuku.
Zotsatira za antihypertensive za Valsartan ndi zamphamvu kuposa za enalapril ndipo ndizoyenera kuchiza matenda oopsa, ofatsa kapena ochepa kwambiri, makamaka matenda oopsa achiwiri omwe amayamba chifukwa cha kuwonongeka kwa aimpso.Ikhoza kuchepetsa kwambiri proteinuria kwa odwala matenda oopsa omwe ali ndi matenda a shuga kapena ntchito yabwino ya chiwindi, ndipo imatha kulimbikitsa uric acid ndi sodium ya mkodzo kuteteza impso.Valsartan ndiyoyeneranso kuchepetsa kufa kwamtima kwa odwala omwe ali pachiwopsezo chachikulu (kulephera kwa ventricular kumanzere kapena kusagwira bwino ntchito) atakumana ndi vuto la mtima.