Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API High Quality
Supply Vonoprazan Fumarate ndi Related Intermediate
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Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Dzina la Chemical | Vonoprazan Fumarate |
| Mawu ofanana ndi mawu | Mtengo wa TAK-438 |
| Nambala ya CAS | 1260141-27-2;881681-01-2 |
| Nambala ya CAT | RF-API99 |
| Stock Status | Mu Stock, Kupanga Kufikira Mazana a Kilogram |
| Molecular Formula | Chithunzi cha C21H20FN3O6S |
| Kulemera kwa Maselo | 461.463 |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Woyera Kapena Wapafupi-Woyera |
| Chizindikiritso 1 H-NMR | Mogwirizana ndi Standard |
| Chizindikiro cha IR | The IR Absorption spectrum ya chitsanzo concordant ndi reference muyezo |
| Chizindikiro cha HPLC | Nthawi yosungira yachitsanzo ikugwirizana ndi mulingo wolozera |
| Mkati mwa Madzi | ≤0.50% |
| Zotsalira pa Ignition | ≤0.20% |
| Zitsulo Zolemera (monga Pb) | ≤20ppm |
| Zogwirizana nazo | |
| Chidetso A | ≤0.20% |
| Chidetso B | ≤0.15% |
| Chidetso C | ≤0.15% |
| Chidetso China Chilichonse | ≤0.10% |
| Zonse Zonyansa | ≤1.0% |
| Zosungunulira Zotsalira | |
| Methanol | ≤0.30% |
| Ethanol | ≤0.50% |
| Ethyl Acetate | ≤0.50% |
| Njira Yoyesera / Kusanthula | 98.0%~102.0% (Wolemba HPLC) |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | API |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi.
Vonoprazan Fumurate (TAK-438) (CAS: 1260141-27-2; 881681-01-2), proton pump inhibitor (PPI), ndi potassium-competitive acid blocker (P-CAB) yamphamvu komanso yogwira pamlomo (P-CAB), yokhala ndi antisecretory. ntchito.Vonoprazan Fumarate imalepheretsa ntchito ya H+,K+-ATPase mu ma microsomes a nkhumba omwe ali ndi IC50 ya 19 nM pa pH 6.5.Vonoprazan Fumarate (Takecab), yomwe inapezedwa ndikupangidwa ndi Takeda ndi Otsuka, inavomerezedwa ndi PMDA ya ku Japan mu December 2014. Vonoprazan Fumarate imagwiritsidwa ntchito makamaka pochiza matenda a helicobacter pylori, gastroesophageal reflux, zilonda zam'mimba, duodenal ulcer, esophagitis, gas. zilonda zam'mimba ndi matenda ena okhudzana ndi asidi am'mimba.Mankhwalawa ali ndi chopinga champhamvu, chokhalitsa cha chapamimba asidi katulutsidwe.Pa mlingo wa chithandizo, Vonoprazan Fumarate ilibe mphamvu pa ma enzymes ena komanso imakhudza pang'ono magwiridwe antchito a thupi.Ndizotetezeka komanso zolekerera.
