OEM manufacturer Esmolol Hydrochloride - Acotiamide Hydrochloride Trihydrate CAS 773092-05-0 API High Purity – Ruifu

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OEM manufacturer Esmolol Hydrochloride - Acotiamide Hydrochloride Trihydrate CAS 773092-05-0 API High Purity – Ruifu Detail:

Manufacturer with High Purity and Stable Quality
Chemical Name: Acotiamide Hydrochloride Trihydrate
CAS: 773092-05-0 
In the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia.
API High Quality, Commercial Production

Chemical Name Acotiamide Hydrochloride Trihydrate 
Synonyms YM-443, Z-338
CAS Number 773092-05-0
CAT Number RF-API34
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C21H31ClN4O5S
Molecular Weight 487.013
Brand Ruifu Chemical
Item Specifications
Appearance White or Off-White Powder
Purity / Analysis Method ≥98.0% (HPLC)
Residual Solvent Ethanol ≤0.50%
Moisture (K.F) 9.0%~12.0%
Individual Impurity ≤0.50%
Total Impurities ≤1.0%
Residue on Ignition ≤0.20%
1H NMR Corresponds to the Structure
Test Standard Enterprise Standard
Usage Active Pharmaceutical Ingredient (API)

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Acotiamide Hydrochloride Trihydrate (CAS: 773092-05-0) with high quality.

Acotiamide, also known as YM-443 and Z-338, is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. It acts as an acetylcholinesterase inhibitor. Note: The Approved drug API is a cotiamide HCl trihydrate (1:1:3). Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor. Acotiamide monohydrochloride trihydrate enhances acetylcholine released by enteric neurons through muscarinic receptor antagonism and acetylcholinesterase (AChE) inhibition, thereby enhancing gastric emptying and gastric accommodation.


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