OEM Supply Ubenimex - Betamethasone CAS 378-44-9 Purity 97.0%~103.0% API High Purity – Ruifu

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OEM Supply Ubenimex - Betamethasone CAS 378-44-9 Purity 97.0%~103.0% API High Purity – Ruifu Detail:

Commercial Supply Betamethasone with High Purity and Stable Quality
Chemical Name: Betamethasone
CAS: 378-44-9
Appearance: White or Almost White Crystalline Powder
Purity: 97.0%~103.0% of C22H29FO5 calculated on the dried basis
Loss on Drying: ≤0.50% 

Chemical Name Betamethasone
CAS Number 378-44-9
CAT Number RF-API12
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C22H29FO5
Molecular Weight 392.47
Brand Ruifu Chemical
Item Specifications
Appearance White or Almost White Crystalline Powder
Identification Complies by IR, TLC
Specific Optical Rotation +118° to +126° (calculated on the dried basis)
Individual Impurity ≤1.0%
Total Impurities ≤2.0%
Residual Solvents Methanol ≤3000ppm
Residual Solvents Chloroform ≤60ppm
Loss on Drying ≤0.50% (Dry it at 105℃, 3 hours)
Residue on Ignition ≤0.20%
Purity 97.0%~103.0% of C22H29FO5 calculated on the dried basis
Test Standard Chinese Pharmacopoeia (CP); EP10.0 and USP 42
Packaging and Storage Preserve in tight containers. Store between 2℃ and 30℃ .
Usage Active Pharmaceutical Ingredient (API)

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Betamethasone, belongs to adrenal corticosteroids, it is a isomer of dexamethasone , and the role of betamethasone is similiar to prednisolone and dexamethasone , it has anti-inflammatory, anti-rheumatic, anti-allergic and suppression of the immune and other pharmacological effects, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone etc. , it can reduce and prevent tissue response to inflammation and eliminate heat, redness and swelling caused by local non-infectious inflammation, thereby reducing the performance of inflammation, anti-inflammatory effect of this product 0.3mg is equal to dexamethasone 0.75mg, prednisone 5mg or 25mg cortisone . Betamethasone sodium retention effect is a hundred times more than hydrocortisone, in primary adrenal hypofunction, it can be used together with glucocorticoid for replacement therapy ,and it is used for preventing or inhibiting cell-mediated immune response, delaying allergic reactions and reducing the primary immune response expansion ,it is used for low renin and low aldosterone syndrome and autonomic neuropathy induced orthostatic hypotension. Currently betamethasone is also used for the treatment of active rheumatoid arthritis, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, atopic dermatitis, eczema, neurodermatitis, seborrheic dermatitis, and pruritus and comprehensive treatment of certain infections. The product is contraindicated in severe psychiatric history, active duodenal ulcer, recent gastrointestinal anastomosis, heavier osteoporosis, overt diabetes, severe hypertension, virus , bacterial, fungal infections which are failed to control by the use of antimicrobial agents , thrombophlebitis, skin infections, such as impetigo, tinea, jock itch and so on.


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