Pantoprazole Sodium CAS 138786-67-1 Purity ≥99.0% (HPLC) API Factory
Chemical Name | Pantoprazole Sodium |
Synonyms | 5-(Difluoromethoxy)-2-(((3,4-Ddimethoxy-2-Pyridinyl)methyl) sulfinyl)-1h-Benzimidazole Sodium |
CAS Number | 138786-67-1 |
CAT Number | RF-API107 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C16H14F2N3NaO4S |
Molecular Weight | 405.35 |
Melting Point | 199.0 to 202.0℃ |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White to Off-White Powder |
Solubility | Free Soluble in Methanol, Ethanol and in Water |
Test for Sodium | To be Positive |
IR Spectrum | Complies With Reference Spectrum |
pH | 9.0~11.5 |
Moisture Content (K.F) | 4.5~8.0% |
Related Substances | HPLC Method |
Major Impurity | ≤0.50% |
Total Impurities | ≤1.0% |
Heavy Metals | ≤20ppm |
Residual Solvents | Meet the Specification |
Assay(by HPLC) | ≥99.0% |
Test Standard | Enterprise Standard |
Usage | API; Proton Pump Inhibitor (PPI) |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
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Pantoprazole Sodium (CAS: 138786-67-1) is an orally active and proton pump inhibitor (PPI) that suppresses the final step in gastric acid production by covalently binding to the (H+, K+)-ATPase enzyme system at the secretory surface of the gastric parietal cell. Pantoprazole sodium, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole is used to treat: Short-Term Treatment of Erosive Esophagitis Associated with Gastroesophageal Reflux Disease (GERD) Maintenance of Healing of Erosive Esophagitis Pathological Hypersecretory Conditions Including Zollinger-Ellison (ZE) Syndrome.
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