Pentafluorophenol CAS 771-61-9 (PFP-OH) Purity ≥99.0% (HPLC) Factory High Purity

Short Description:

Chemical Name: Pentafluorophenol  

Synonyms: PFP-OH

CAS: 771-61-9

White Low Melting Point Crystal Solid

Purity: ≥99.0% (HPLC)

High Quality, Commercial Production 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com 


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Pentafluorophenol (CAS: 771-61-9) with high quality, mass production. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase Pentafluorophenol, Please contact: alvin@ruifuchem.com

Chemical Properties:

Name Pentafluorophenol
Synonyms 2,3,4,5,6-Pentafluorophenol; Perfluorophenol; PFP; PFP-OH
CAS Number 771-61-9
Stock Status In Stock, Mass Production
Molecular Formula C6HF5O
Molecular Weight 184.07
Condition to Avoid Air Sensitive
Melting Point 34.0~36.0℃(lit.)
Boiling Point 143℃(lit.)
Density  1.757
Solubility in Water Slightly Soluble in Water
COA & MSDS Available
Category   Coupling Reagents 
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White Low Melting Point Crystal Solid
Purity / Analysis Method ≥99.0% (HPLC)
Melting Point 34.0~36.0℃
Water by Karl Fischer  ≤0.50%
Residue on Ignition ≤0.20%
Single Impurity ≤0.50%
Total Impurities ≤1.00%
Heavy Metals ≤20ppm
Infrared Spectrum Conforms to Structure
Proton NMR Spectrum  Conforms to Structure
Test Standard Enterprise Standard
Attention Protect from the light and store in a cool and dry place (2~8℃)
Note This product is low melting point solid, may change state in different environments (solid, liquid or semi-solid)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

1

FAQ:

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771-61-9 - Risk and Safety:

Risk Codes
R36/37/38 - Irritating to eyes, respiratory system and skin.
R34 - Causes burns
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R63 - Possible risk of harm to the unborn child
R43 - May cause sensitization by skin contact
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
R45 - May cause cancer
R67 - Vapors may cause drowsiness and dizziness
R40 - Limited evidence of a carcinogenic effect
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S36/37 - Wear suitable protective clothing and gloves.
S24/25 - Avoid contact with skin and eyes.
S23 - Do not breathe vapour.
S53 - Avoid exposure - obtain special instructions before use.
UN IDs 2811
WGK Germany 3
RTECS SM6680000
FLUKA BRAND F CODES 3
TSCA T
HS Code 2908199090
Hazard Note Toxic/Irritant
Hazard Class 8
Packing Group III
Toxicity LD50 scu-rat: 322 mg/kg IZSBAI 3,91,65

Application:

Pentafluorophenol (CAS: 771-61-9) can be used for the preparation of penta-fluorophenyl esters for peptide synthesis. It is used in the preparation of pentafluorophenyl esters for peptide synthesis and vulcanized polymers. It is also used for peptide coupling and heterocyclic acid derivatives. It is involved in the preparation of pentafluorophenyl formate which acts as a formulating agent for amines and amino acids. It can be used for synthesizing novel reagents which can achieve highly diastereoselective acetal cleavage.
Pentafluorophenol is also the intermediate of Sofosbuvir in the treatment of Hepatitis C Virus (HCV).
Pentafluorophenol is a polyfluoro liquid crystal compound with small steric hindrance, which is an important intermediate for the preparation of high performance liquid crystal materials, it is especially suitable for the preparation of polyfluoro monomer liquid crystal materials. After the polyfluoro monomer liquid crystal materials are mixed with low viscosity and high dielectric anisotropy nematic liquid crystal materials, the dipole distance of molecules can be increased, reducing the response time, improving the display performance of the liquid crystal material, increasing the clarity, has an important meaning to the production of high performance liquid crystal materials.
Pentafluorophenol is an important intermediate, mainly used in the preparation of pharmaceutical, liquid crystal and polymer materials intermediates, such, in the field of medicine and pesticide, pentafluorophenol is used to prepare pentafluorophenyl active ester for peptide synthesis, thus promoting the formation of peptide, pentafluorophenyl ester can be used for solid phase synthesis of peptides, it can also be used for liquid phase synthesis, and can also be used as a protecting group for an amino acid protecting group alkyl ester or sulfonic acid group.

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