Phenylhydrazine CAS 100-63-0 Purity >99.0% (GC)

Phenylhydrazine (CAS: 100-63-0), is also known as the Hydrazinobenzene. It was first successfully synthesized by the German organic chemist Hermann-Emil-Fischer in 1875 and is the first synthesized hydrazine derivatives. It can be easily subject to oxidization in the air and exhibit dark brown or dark red. Phenylhydrazine can often be used as intermediates of organic dyes, pharmaceuticals and pesticide. It can also be used as organic intermediates for synthesis of pyrazoline, triazole, and indole; It can also be used as dye intermediates like disazo dye intermediates such as 1-phenyl-3-methyl-5-pyrazolone and so on; It can also be used as pharmaceutical intermediates for preparation of antipyretic, analgesic, anti-inflammatory drugs such as antipyrine and aminopyrine, etc; it can also be used as photography drugs (photosensitive dye); Phenylhydrazine is also the raw material for the production of pesticides "imputed phosphorus"; Phenylhydrazine is used as a stabilizer for explosives; as a reagent for aldehydes, ketones and sugars in chemical analysis; in organic synthesis. Reagents for Preparing Animal Disease Models. Used in the synthesis of dyes and other organic substances. Mainly used in the production of azoic coupling component AS-G. Phenylhydrazine is involved in Fischer indole synthesis to prepare indoles, which find application as intermediates in the pharmaceuticals particularly for the tryptamine drug. In analytical chemistry, it is used to differentiate and separate sugars by forming phenyhydrazones. It is used as an N-protecting reagent and for cleavage of phthaloyl group. Phenylhydrazine is also used as an analytical reagent. It is also an important reagent for identification of carbonyl group and can be used for identifying aldehydes, ketones and carbohydrates. It can react with benzaldehyde to generate phenylhydrazine. Common method of its preparation is through the reaction between aniline and sodium nitrite under the action of hydrochloric acid for generation of diazonium salt which is then reduced by sulfite/sodium reduction for obtaining it. Acid precipitation can generate phenylhydrazine hydrochloride with neutralization generating phenylhydrazine.