Pimasertib (AS-703026) CAS 1236699-92-5 Purity >99.0% (HPLC) MEK1/2 Inhibitor

Short Description:

Chemical Name: Pimasertib 

Synonyms: AS-703026

CAS: 1236699-92-5

Purity: >99.0% (HPLC)

Appearance: Yellow Solid

MEK1/2 Inhibitor, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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1236699-92-5 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Pimasertib (AS-703026) (CAS: 1236699-92-5) with high quality. Ruifu Chemical has been supplying pharmaceutical intermediates and APIs more than 15 years. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Pimasertib (AS-703026) or other products, please contact us by e-mail: alvin@ruifuchem.com

1236699-92-5 - Chemical Properties:

Chemical Name Pimasertib
Synonyms AS-703026; AS 703026; AS703026; MSC1936369B; SAR-245509; SAR245509; N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]-4-pyridinecarboxamide; N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide; (S)-N-(2,3-Dihydroxypropyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide
Stock Status In Stock
CAS Number 1236699-92-5
Molecular Formula C15H15FIN3O3
Molecular Weight 431.2 g/mol
Melting Point 164.0~169.0℃ 
Density 1.769
Refractive Index n20/D 1.684
Solubility  DMSO 86 mg/mL
Storage Temperature Store Long-Term at -20℃
Shipping Conditions Shipped Under Ambient Temperature for Short Term
COA & MSDS Available
Origin of Product    Shanghai, China
Application(s)
MEK1/2 Inhibitor  
Caution Not For Human or Veterinary Use. For Research Use Only.
Brand Ruifu Chemical

1236699-92-5 - Specifications:

Items Specifications  Results
Appearance Yellow Solid  Yellow Solid 
Pimasertib Purity  >99.0% (HPLC)  99.7%
1H NMR Spectrum Consistent with Structure  Conforms   
LC-MS Consistent with Structure Conforms   
Conclusion The product has been tested and complies with the given specifications

1236699-92-5 - Package/Storage/Shipping:

Package: Bottle, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store long-term at -20℃. Keep away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

1236699-92-5 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

1236699-92-5 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

1236699-92-5 - Application:

Pimasertib (AS-703026) (CAS: 1236699-92-5) is a potent, selective, and ATP-noncompetitive allosteric inhibitor of MEK1/2, primarily for cancer research.  
Pimasertib is a novel, small-molecule, dual inhibitor of MEK and PI3K/mTOR. It is a promising drug candidate for the treatment of a variety of cancers, including colon, breast, ovarian, and pancreatic cancer. Pimasertib has a unique mechanism of action, which is thought to be synergistic with other cancer treatments.

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